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Overexpression of PGC1 in vascular smooth muscle cells ameliorates atherosclerosis In a new study published in Circulation Research, Chen-Yu Zhang and Xiaohong Jiang s group from Nanjing University and Dongjin Wang s group from Nanjing Drum Tower Hospital reported a critical role of PGC1α in maintaining the contractile phenotype of vascular smooth muscle cells (VSMCs) and highlighted the therapeutic potential of PGC1α for atherosclerosis. The traditional view holds that aberrant proliferation of VSMCs promotes plaque formation after vessel injury and inflammation, whereas the presence of VSMCs in the fibrous cap of the plaque is beneficial. Although it has long been assumed that these seemingly contradictory functions of VSMCs during atherosclerosis arise from their remarkable plasticity, direct evidence that VSMCs undergo phenotypic switching during atherogenesis in vivo has only been proven recently by rigorous lineage tracing studies. ....
Smooth muscle overexpression of PGC1α attenuates atherosclerosis in rabbits eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
These Asian American health care workers are fighting two viruses: Covid and hate 989thevibe.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from 989thevibe.com Daily Mail and Mail on Sunday newspapers.
These Asian American health care workers are fighting two viruses: Covid and hate kaok.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from kaok.com Daily Mail and Mail on Sunday newspapers.
(PRNewsfoto/Apollo Medical Holdings, Inc.) ALHAMBRA, Calif. and NEW YORK, Jan. 26, 2021 /PRNewswire/ Apollo Medical Holdings, Inc. ( ApolloMed ) (NASDAQ: AMEH), a leading physician-centric, technology-powered healthcare management company, and CAIPA MSO, LLC ( CAIPA MSO ), a management services organization based out of New York, today announced a strategic alliance and investment by ApolloMed in CAIPA MSO. CAIPA MSO provides management, consulting, administrative, and other support services to professional healthcare service providers, including to Chinese American IPA d/b/a Coalition of Asian-American IPA ( CAIPA ), a leading independent practice association serving the greater New York City area. With over 1,000 private practice providers covering over 70 specialties, CAIPA s provider network provides medical services and care to approximately 500,000 patients. CAIPA is consistently one of the top performing provider networks in the region in quality and value-bas ....