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Fresh insight into protein production inside brain cells could help tackle Parkinson s

 E-Mail Wednesday 19 May 2021 - New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions. In a study part-funded by Parkinson s UK, researchers investigated a section of genetic material known as antisense long non-coding RNA (lncRNA), which helps fine-tune the production of the protein tau inside brain cells. This precision in tau regulation is crucial for smooth functioning of the nerve cells. Understanding the mechanism which helps regulate tau production could be the key to developing better treatments for conditions including Parkinson s, Alzheimer s, corticobasal degeneration and progressive supranuclear palsy.

New insight into protein production in brain could help tackle dementia

 E-Mail A pioneering new study led by UCL scientists has revealed, for the first time, a layer of genetic material involved in controlling the production of tau; a protein which plays a critical role in serious degenerative conditions, such as Parkinson s and Alzheimer s disease. The international research, conducted in mice and cells, also revealed this material is part of a larger family of non-coding genes which control and regulate other similar brain proteins, such as beta-amyloid associated with Alzheimer s and alpha-synuclein implicated in Parkinson s disease and Lewy body dementia. Researchers say the breakthrough findings, published in Nature, shed an important new light on how proteins linked to neurological conditions are produced and controlled, and could pave the way for new treatments for a wide range of dementia related diseases.

Seafood company makes big purchase

Seafood company makes big purchase Updated 7:18 AM; Ren Seafoods paid $4.17 million for the former Smith’s Bakery building and property at 1201 West I-65 Service Road N. in Mobile, according to Marietta Urquhart and Jamie Ison of White-Spunner Realty, who represented the buyer. David Dexter of CRE Mobile worked for the sellers. Ren Seafoods plans to invest $12.4 million to develop a processing facility and distribution hub. The property includes 15.64 acres with a 70,130-square-foot production area; a cross dock of 35,685 square feet; and a 4,826-square-foot truck service facility. Frios Gourmet Pops leases about 30,000 square feet of the building that was used by the bakery for storage and distribution.

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