Chalmers University of Technology
The ease by which mRNA-based drugs are taken up by cells in tissues is crucial to their therapeutic effectiveness. Now, a new detection method developed by researchers at Chalmers and AstraZeneca could lead to faster and better development of the small droplets known as lipid nanoparticles, which are the main method used to package mRNA for delivery to the cells.
“We have developed an automated process to monitor and test large numbers of different lipid nanoparticles simultaneously, which we hope will streamline the development of new medicines,” says Michael Munson, Postdoctoral Fellow at AstraZeneca R&D, who is affiliated to the research centre FoRmulaEx, and is the first author of the study that was recently published in the journal Nature Communications Biology.
Researchers monitor mRNA to help time its great escape to perfection The ease by which mRNA-based drugs are taken up by cells in tissues is crucial to their therapeutic effectiveness. Now, a new detection method developed by researchers at Chalmers University of Technology, Sweden, and AstraZeneca could lead to fast.
In an international collaboration including EPFL, scientists have achieved giant nonlinearity of UV hybrid light-matter states up to room temperature in a waveguide made of AlInGaN, a wide bandgap semiconductor. The achievement paves the way for new devices in ultrafast chemical and biochemical spectroscopy.
/PRNewswire/ Jeannie Diefenderfer has been named chief executive officer of the Center for Higher Ambition Leadership (CHL), a non-profit community formed.