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Chalmers University of Technology ​​The ease by which mRNA-based drugs are taken up by cells in tissues is crucial to their therapeutic effectiveness. Now, a new detection method developed by researchers at Chalmers and AstraZeneca could lead to faster and better development of the small droplets known as lipid nanoparticles, which are the main method used to package mRNA for delivery to the cells.​ “We have developed an automated process to monitor and test large numbers of different lipid nanoparticles simultaneously, which we hope will streamline the development of new medicines,” says Michael Munson, Postdoctoral Fellow at AstraZeneca R&D, who is affiliated to the research centre FoRmulaEx, and is the first author of the study that was recently published in the journal Nature Communications Biology.

Vastra gotalands lanKarolinska institutetMichael munsonElin esbjUniversity of gothenburgChalmers university of technologyNature communications biologyChalmers universityPostdoctoral fellowNature communicationsAssociate professorChemical biologyUniversity of gothenburgKarolinska institutetNature communicationsChronic disease