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Research from Chalmers heading for Silicon Valley

Research from Chalmers heading for Silicon Valley
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Elin esbjMarcus wilhelmssonChristoph langhammerDepartment of chemistryDepartment of physicsRoyal swedish academy of engineering sciencesDepartment of biologySilicon valleyRoyal swedish academyEngineering sciencesChemical engineeringAssociate professorBiological engineeringFull professorEnvue technologies

Breakthrough for tracking RNA with fluorescence

Breakthrough for tracking RNA with fluorescence
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United statesFrance generalElin esbjMarcus wilhelmssonDepartment of chemistryJournal of the american chemical societyChemical engineering at chalmers university of technologyPasteur instituteDepartment for biologyAmerican chemical societyChemical engineeringChalmers universityAssociate professorஒன்றுபட்டது மாநிலங்களில்துறை ஆஃப் வேதியியல்இதழ் ஆஃப் தி அமெரிக்கன் இரசாயன சமூகம்

Breakthrough method for tracking mRNA molecules with fluorescence

Breakthrough method for tracking mRNA molecules with fluorescence Researchers at Chalmers University of Technology, Sweden, have succeeded in developing a method to label mRNA molecules, and thereby follow, in real time, their path through cells, using a microscope - without affecting their properties or subsequent activity. The breakthrough could be of great importance in facilitating the development of new RNA-based medicines. RNA-based therapeutics offer a range of new opportunities to prevent, treat and potentially cure diseases. But currently, the delivery of RNA therapeutics into the cell is inefficient. For new therapeutics to fulfil their potential, the delivery methods need to be optimised. Now, a new method, recently presented in the highly regarded

United statesFrance generalElin esbjMarcus wilhelmssonEmily hendersonResearchers at chalmers university of technologyChemical engineering at chalmers university of technologyPasteur instituteDepartment for biologyRoyal swedish academy of engineering sciencesDepartment of chemistryChalmers innovation officeJournal of the american chemical societyChalmers universityAmerican chemical societyChemical engineering

Breakthrough for tracking RNA with fluorescence

Breakthrough for tracking RNA with fluorescence
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United statesFrance generalElin esbjMarcus wilhelmssonResearchers at chalmers university of technologyChemical engineering at chalmers university of technologyPasteur instituteDepartment for biologyRoyal swedish academy of engineering sciencesDepartment of chemistryChalmers innovation officeJournal of the american chemical societyChalmers universityAmerican chemical societyChemical engineeringAssociate professor

Monitoring mRNA to time its great escape perfectly

Chalmers University of Technology The ease by which mRNA-based drugs are taken up by cells in tissues is crucial to their therapeutic effectiveness. Now, a new detection method developed by researchers at Chalmers and AstraZeneca could lead to faster and better development of the small droplets known as lipid nanoparticles, which are the main method used to package mRNA for delivery to the cells. “We have developed an automated process to monitor and test large numbers of different lipid nanoparticles simultaneously, which we hope will streamline the development of new medicines,” says Michael Munson, Postdoctoral Fellow at AstraZeneca R&D, who is affiliated to the research centre FoRmulaEx, and is the first author of the study that was recently published in the journal Nature Communications Biology.

Vastra gotalands lanKarolinska institutetMichael munsonElin esbjUniversity of gothenburgChalmers university of technologyNature communications biologyChalmers universityPostdoctoral fellowNature communicationsAssociate professorChemical biologyUniversity of gothenburgKarolinska institutetNature communicationsChronic disease