Double whammy inflates gastric cancer risk by 45% miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Individuals with inherited pathogenic variants in genes associated with homologous recombination of DNA who also had H pylori infections had a 3-fold higher risk for gastric cancer vs infected noncarriers.
A large case-control study by RIKEN in Japan has found that people who carry certain genetic risk factors for gastric (stomach) cancer have a much greater risk if they have also been infected by the bacterium Helicobacter pylori. The study could contribute to the development of tailored genomic medicine for treating stomach cancer.
Pathogenic Genetic Variations Increase Risk of H Pylori-Related Stomach Cancer miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Individuals with certain germline pathogenic variants had a substantially higher risk for developing gastric cancer after Helicobacter pylori infection, results of a Japan-based case-control study showed.The findings, published in The New England Journal of Medicine, suggest risk for gastric cancer is more heavily related to hereditary factors than previously thought, the investigators noted.