1. The following genes had statistically significant increased odds ratio of gastric cancer; BRCA2, ATM, BRCA1, MLH1, PALB2, APC, MSH6, MSH2, CDH1. 2. Patients with H. pylori infection and a pathogenic variant had a higher cumulative risk of gastric cancer than noncarriers infected with H. pylori (45.5% vs. 14.4%) at 85 years of age. Evidence
A large case-control study by RIKEN in Japan has found that people who carry certain genetic risk factors for gastric (stomach) cancer have a much greater risk if they have also been infected by the bacterium Helicobacter pylori. The study could contribute to the development of tailored genomic medicine for treating stomach cancer.
Pathogenic Genetic Variations Increase Risk of H Pylori-Related Stomach Cancer miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.