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 E-Mail Wednesday 19 May 2021 - New research published today sheds important light on how the production of a key protein in the brain is controlled, which could pave the way for new treatments for a wide range of neurological conditions. In a study part-funded by Parkinson s UK, researchers investigated a section of genetic material known as antisense long non-coding RNA (lncRNA), which helps fine-tune the production of the protein tau inside brain cells. This precision in tau regulation is crucial for smooth functioning of the nerve cells. Understanding the mechanism which helps regulate tau production could be the key to developing better treatments for conditions including Parkinson s, Alzheimer s, corticobasal degeneration and progressive supranuclear palsy.

United kingdomDavid dexterRoberto simoneUniversity college londonUniversity of trentoKarolinska instituteFrancis crick instituteResearch at parkinson united kingdomProfessor rohan de silvaAssociate directorParkinsons diseaseஒன்றுபட்டது கிஂக்டம்டேவிட் டெக்ஸ்டர்ரொபெர்டோ சிமோன்பல்கலைக்கழகம் கல்லூரி லண்டன்பல்கலைக்கழகம் ஆஃப் ட்ரெண்டோ