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The RCT Controversy

By Lars P. SyllCauses deduced in an experimental setting still have to show that they come with an export-warrant to the target population/system. The causal background assumptions made have to be justified, and without licenses to export, the value of ‘rigorous’ and ‘precise’ methods - and ‘on-average-knowledge’ - is despairingly small. ....

Stephen Senn , Angus Deaton Nancy Cartwright , Noelle Otto , Deaton Cartwright , Andrew Gelman , Social Science , Angus Deaton , Nancy Cartwright , Controlled Trials , Close Up Photography , Magnifying Glass , Larsp Syll , Economic Theory , Randomized Controlled Trials , Angus Deaton , Nancy Cartwright , Average Treatment Effect , Stephen Senn , Andrew Gelman , Maginative Empirical Methods , Natural Experiments , Field Experiments , Lab Experiments , Cause And Effect , Davida Freedman , ஸ்டீபன் சென்ன் ,

The Pioneering Crossover Trials for Covid Vaccines and What We'll Find Out


Absolutely Maybe
As results for the big phase 3 trials for the BNT-Pfizer and Moderna were looming, a debate ramped up: when would the thousands of people in their placebo groups get vaccinated? That debate got
really intense when we saw how effective those vaccines looked, and how bad the Covid pandemic was getting.
How do you weigh up the value of the critical information you would get from continuing the blinded trials – we only had very short-term efficacy and safety data when they delivered first results – versus not penalizing the group of people who had volunteered? If you didn’t offer them vaccination, they’d be waiting up to two years, at the end of the vaccine queue. And ....

United Kingdom , New York , United States , Carl Zimmer , Stephen Senn , Steven Goodman , Noah Weiland , Anthony Fauci , Kate Pullinger , New York Times , Over Trials In Clinical Research , Statistically Funny , Dean Follmann , Latin American , Cross Over Trials , ஒன்றுபட்டது கிஂக்டம் , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , கார்ல் ஸிம்மர் , ஸ்டீபன் சென்ன் , ஸ்டீவன் நல்ல மனிதன் , நோவா வெயிலாண்ட் , புதியது யார்க் முறை , ஓவர் சோதனைகள் இல் மருத்துவ ஆராய்ச்சி , லத்தீன் அமெரிக்கன் , குறுக்கு ஓவர் சோதனைகள் ,