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Tissue stiffness likely drives immune responses in many chronic diseases


 E-Mail
Stiffness in our tissues causes tension in our cells. Research from the Buck Institute, the University Health Network (University of Toronto), Stanford University, and the University of Alberta shows that stiffness impacts the innate immune system by upping its metabolism. The findings suggest the cellular tension likely sets off an inflammatory loop that contributes to the development of chronic diseases of aging. Publishing in
Cell Reports, Buck Associate Professor Dan Winer, MD, and colleagues present an emerging way of looking at how the immune system functions, possibilities for new immunotherapeutics, and a call for scientists to reconsider the way they do research. ....

Stanford University , United States , Palo Alto , Yi Tao Chan , Evangelos Michelakis , Mainak Chakraborty , Chiara Pastrello , Cynthia Goh , Dan Winer , Los Angeles , Fanta Barrow , Xiangyue Zhang , Megan Lee , Shawn Winer , Edgarg Engleman , Pamelas Ohashi , Aventis Pasteur , Xavier Clemente Casares , Saad Khan , Igor Jurisica , Nicholask Kotoulas , Juan Jovel , Camille Huang , Annie Shrestha , Xaviers Revelo , Masoud Akbari ,

IDFA 2020 Part 3: SHE HAD A DREAM, JACINTA, THE MOLE AGENT And SHOWGIRLS OF PAKISTAN


She Had a Dream (Raja Amari)
Bearing a title similar to that of MLK’s most famous speech,
She Had a Dream is an inspiring story about how a woman turned pain into power.
Tunisian filmmaker
Raja Amari, transitioning from narrative features to documentary, pays attention to the life of Ghofrane Binous, a 25-year-old activist who pursues her political aspiration by running for office during Tunisia’s 2019 national elections. All the odds are against Binous to succeed – Black, working-class, woman – something she realised so young when the kids at school would mock her for her skin colour. She hasn’t suffered discrimination in her own neighbourhood however she admits encountering casual prejudice by the privileged folks of Tunis. The sort of liberal racism that was highlighted in ....

United States , United Arab Emirates , North West Frontier , Noord Holland , Youssef Chahed , Maite Alberdi , Jacinta Jessica Earnshaw , Ghofrane Binous , Jessica Earnshaw , Saad Khan , Raja Amari , Amsterdam International Documentary Film Festival , International Documentary Film Festival , She Had , Prime Minister Youssef Chahed , Mole Agent , James Bond Esque , ஒன்றுபட்டது மாநிலங்களில் , ஒன்றுபட்டது அரபு அமீரகங்கள் , வடக்கு மேற்கு எல்லை , நூற்த் ஹாலண்ட் , ஜசிந்தா ஜெசிகா அர்ந்ஶே , ஜெசிகா அர்ந்ஶே , ஸாட் காந் , ராஜா அமரி , ஆம்ஸ்டர்டாம் சர்வதேச ஆவணப்படம் படம் திருவிழா ,

Southern Punjab 2nd XI win Pakistan One-day Cup


Sports
December 25, 2020
KARACHI: Southern Punjab won the Pakistan One-day Cup for 2nd XI after emerging as leaders on the points table here on Thursday.
Southern Punjab in their last outing defeated Khyber Pakhtunkhwa by eight wickets to finish with eight points.
Sindh also ended with eight points but Southern Punjab clinched the title on the basis of better net run-rate.
The event was conducted under a single league system among the six outfits.
Here at NBP Sports Complex, Khyber Pakhtunkhwa posted 248 all out in 46.3 overs. Opener Mohammad Mohsin Khan top-scored with 65 off 77 balls, hammering seven fours and one six. Sahibzada Farhan contributed 45 off 64 balls, smacking six fours. Ahsan Baig took three wickets, while Mukhtar Ahmed and Zohaib Afridi claimed two wickets apiece. ....

Faraz Ali , Mohammad Mohsin Khan , Mehran Mumtaz , Hassan Khan , Mukhtar Ahmad , Zohaib Afridi , Mukhtar Ahmed , Waqar Hussain , Salman Irshad , Shoaib Ahmed , Junaid Ali , Aaamer Jamal , Saad Khan , Fahad Hussain , Ziad Khan , Rameez Aziz , Abdul Wahid Bangalzai , Sahibzada Farhan , Ahsan Baig , Southern Punjab , Pakistan One Day Cup , Khyber Pakhtunkhwa , Central Punjab , பாராஜ் அலி , முகமது மொஹசின் காந் , மெஹ்ரான் மம்டஸ் ,

Sindh, Northern, KP register victories in Pakistan Cup


Sindh, Northern, KP register victories in Pakistan Cup
Sports
December 21, 2020
KARACHI: Sindh, Northern and Khyber Pakhtunkhwa on Sunday registered victories in the third round of the Pakistan Cup One-Day Tournament 2020-21 for Second XI here at different venues.
At KCCA Stadium, Khyber Pakhtunkhwa recorded a 126-run win over Balochistan. Khyber Pakhtunkhwa scored 262 for the loss of seven wickets in their allotted 50 overs.
Sahibzada Farhan top-scored with 53 off 88 balls (four fours, one six). Mehran Ibrahim contributed 50 off 59 balls (four fours). Ashfaq Ahmed scored 49 runs. Zainullah took three wickets for 55.
In reply, Balochistan were rolled over for 136 runs in 34.5 overs. Abdul Rehman Muzammil top-scored with 53 off 81 balls (three fours, one six). No other batsman offered any sustained resistance against the Khyber Pakhtunkhwa bowling attack. Maaz Sadaqat took three wickets for 21, while Asad Afridi took two for eight in 2.5 overs. ....

Mehran Ibrahim , Jahanzaib Sultan , Pacer Aamer Jamal , Mohammad Junaid , Ashfaq Ahmed , Mukhtar Ahmed , Waqar Hussain , Salman Irshad , Shoaib Ahmed , Mohammad Alam , Umar Waheed , Saad Khan , Abdul Rehman Muzammil , Asad Afridi , Raza Ali Dar , Rameez Aziz , Sahibzada Farhan , Ahsan Baig , Khyber Pakhtunkhwa , Pakistan Cup One Day Tournament , Rehman Muzammil , Southern Punjab , Aaamer Jamal , Central Punjab , Haseeb Ur Rehman Junior , Ali Dar ,

The IPG Group Bags Exclusive Rights for Singapore T10


The IPG Group Bags Exclusive Rights for Singapore T10
Singapore Cricket Association (SCA) has awarded the marketing and organizing rights for the SCA T10 Cricket to Dubai/Pakistan based Innovative Production Group (IPG). Five companies had submitted expression of interest (EOI) after SCA had floated an RFP (request for proposal) for the sale of rights in August this year.
The IPG Group has emerged as the highest bidder for the rights. This is the second major cricket league for which the IPG Group has bagged the rights after the successful Lanka Premier League (LPL) in Sri Lanka.
A virtual contract signing ceremony was hosted jointly by SCA and IPG Group in compliance with Covid guidelines on 16th December 2020 where SCA President Mr Mahmood Gaznavi signed the contract documents on behalf of host Governing Body SCA in the presence of Deputy President Mr Subir Ghatak, Vice Presidents Mr Manesh M and Mr S Santhanam, Hon. Tresurer Mr Neeraj S and CEO of the SCA Mr Saad Kh ....

South Africa , United Arab Emirates , New Zealand , Sri Lanka , Saad Khan Januja , Mahmood Gaznavi , Jawad Ghulam Rasool , Saad Khan Janjua , Subir Ghatak , Innovative Production Group , Lanka Premier League , Singapore Cricket Association , Governing Body , Deputy President Mr Subir Ghatak , Saad Khan , Cricket Association , ஒன்றுபட்டது அரபு அமீரகங்கள் , புதியது ஜீலாந்து , ஸ்ரீ லங்கா , மஹ்மூத் கஜ்நாவி , ஜவாத் குலாம் ரசூல் , ஸாட் காந் ஜ்யாஂஜ்யூயே , சுபிர் ஏட்யாக் , புதுமையானது ப்ரொடக்ஶந் குழு , லங்கா ப்ரிமியர் லீக் , சிங்கப்பூர் மட்டைப்பந்து சங்கம் ,