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More Support for Gene Assay to Guide Breast Cancer Treatment

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Patients with ultralow-risk breast cancer according to genomic assessment had excellent long-term outcomes regardless of clinical risk or whether they received adjuvant therapy, a new analysis of a randomized trial showed.
The 8-year breast cancer-specific survival (BCSS) was 99.2% among patients classified as clinically high-risk but ultralow-risk by the MammaPrint 70-gene assay. Patients with an ultralow-risk genomic assessment and low clinical risk had an 8-year BCSS of 99.7%. Freedom from distant metastasis at 8 years was 97.6% in patients who were clinically and genomically low-risk versus 95.0% for those who were clinically high-risk but genomically low-risk.
In patients with an ultralow-risk genomic assessment, the 8-year distant metastasis-free interval (DMFI) rate was 97.8% with no adjuvant systemic therapy. That compared with an 8-year DMFI of 97.4% in patients who received only adjuvant endocrine therapy and 94.9% in patients who received ....

United States , Noord Holland , Priya Rastogi , Charles Bankhead , Josephine Lopes Cardozo , National Surgical Adjuvant Breast , American Society Of Clinical Oncology , University Of Pittsburgh , Netherlands Cancer Institute , American Society , Clinical Oncology , Surgical Adjuvant Breast , Bowel Project , Medpage Today , Endocrine Therapy , Breast Cancer , ஒன்றுபட்டது மாநிலங்களில் , நூற்த் ஹாலண்ட் , பிரியா ரஸ்டோகி , சார்லஸ் வங்கித் தலை , ஜோசபின் லோப்ஸ் கார்டோசோ , அமெரிக்கன் சமூகம் ஆஃப் மருத்துவ புற்றுநோயியல் , பல்கலைக்கழகம் ஆஃப் பிட்ஸ்பர்க் , நெதர்லாந்து புற்றுநோய் நிறுவனம் , அமெரிக்கன் சமூகம் , மருத்துவ புற்றுநோயியல் ,

Wrestler Heiki Nabi tests positive for doping

Two-time world champion and Olympic silver medalist wrestler Heiki Nabi tested positive for letrozole, a drug prohibited by the World Anti-Doping Agency.
The 35-year old Nabi tested positive for the illegal substance letrozole in the start of the year, a medicine used to accelerate muscle growth and development. Nabi is now under a primary competition ban, as of Wednesday.
I was and still am shocked! I sincerely cannot imagine how a substance such as this ended up in my organism. The lack of knowledge in this situation is most hurtful. With my hand on my heart - I have always followed fair play rules when doing sports, said Nabi via a press release. When I heard the substance is found in women s breast cancer medicines, my bewilderment grew larger. ....

Andreas Veerpalu , Karel Tammj , Ivar Kotkas , Mark Schmidt , Heiki Nabi , Jaanika Kaljola , Eesti Ekspress , Andrus Veerpalu , Estonian Center , Culture Anneli Ott Center , Estonian Wrestling Federation , Estonian Anti Doping Agency , Kristjan Port , Wrestling Federation , Culture Anneli Ott , Seefeld Ski Championships , Mati Alaver , Greco Roman Wrestling , Olympic Games , குறி ஶ்மிட் , எஸ்டோனியன் மையம் , எஸ்டோனியன் மல்யுத்தம் கூட்டமைப்பு , கிறிஸ்ட்ஜன் போர்த் , மல்யுத்தம் கூட்டமைப்பு , க்ரெகொ ரோமன் மல்யுத்தம் , ஒலிம்பிக் விளையாட்டுகள் ,