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With a ‘liquid assembly line,’ Penn researchers have produced mRNA-delivering-nanoparticles significantly faster than standard microfluidic technologies. The COVID vaccines currently being deployed were developed with unprecedented speed, but the mRNA technology at work in some of them is an equally impressive success story. Because any desired mRNA sequence can be synthesized in massive quantities, one of the biggest hurdles in a variety of mRNA therapies is the ability to package those sequences into the lipid nanoparticles that deliver them into cells. The researchers’ new platform technology, called Very Large Scale Microfluidic Integration, allows tens of thousands of microfluidic units to be incorporated into a single three-dimensionally etched silicon-and-glass wafer. (Image: Penn Engineering Today) ....
Three Iowa colleges highlight research in housing, genetics, chemistry From housing markets to genetic inheritance to molecular delivery vehicles: Get to know three research projects led by Iowa professors that could play a big role in our future world. Researchers study effects of landlord decisions during pandemic Iowa State University Researchers at the ISU College of Design and College of Liberal Arts and Sciences received a $60,000 National Science Foundation rapid response grant to study how landlord decision-making influenced regional housing markets during the COVID-19 pandemic. RESEARCHERS: Jane Rongerude, associate professor of community and regional planning; Biswa Das, associate professor of community and regional planning, specialist with ISU Extension and Outreach; Daniel Kuhlmann, assistant professor of community and regional planning; Lily Wang, professor of statistics; Lin Quan, Ph.D. statistics student. ....