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Cell therapy improves outcomes for heart failure patients, clinical trial shows A clinical trial conducted at the University of Louisville has shown for the first time that heart failure treatments using cells derived from the patient s own bone marrow and heart resulted in improved quality of life and reduced major adverse cardiac events for patients after one year. This is a very important advance in the field of cell therapy and in the management of heart failure. It suggests that a treatment, given only once, can produce long-term beneficial effects on the quality of life and prognosis of these patients. The results pave the way for a larger, Phase 3 trial of cell therapy in heart failure. ....
Clinical trial shows cell therapy improves clinical outcomes in heart failure eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Clinical trial at UofL shows cell therapy improves outcomes in heart failure uoflnews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from uoflnews.com Daily Mail and Mail on Sunday newspapers.
May 27, 2021 Biomarker synthesized by Th17 cells appears to differentiate myocarditis from MI Differentiating acute myocarditis from myocardial infarction (MI) requires either an invasive biopsy or cardiac MRI technology that is not always available so the possibility that a microRNA biomarker in circulating T cells could be used to confirm myocarditis is appealing. Identifying that novel miRNA was the goal of Rafael Blanco-Dominguez, MSc, of the Vascular Pathophysiology Area, Centro Nacional de Investigaciones Cardiovasculares in Madrid, and a team of international researchers, who started by inducing autoimmune myocarditis or myocardial infarction in mice to identify the microRNA found in Th17 cells in plasma of mice with acute myocarditis either autoimmune or virus-induced. ....
Multi-institutional team combined expertise to make discovery May 17, 2021 SHARE Dozens of commonly used drugs, including antibiotics, anti-nausea and anticancer medications, have a potential side effect of lengthening the electrical event that triggers contraction, creating an irregular heartbeat, or cardiac arrhythmia called acquired Long QT syndrome. While safe in their current dosages, some of these drugs may have a more therapeutic benefit at higher doses, but are limited by the risk of arrhythmia. Through both computational and experimental validation, a multi-institutional team of researchers has identified a compound that prevents the lengthening of the heart’s electrical event, or action potential, resulting in a major step toward safer use and expanded therapeutic efficacy of these medications when taken in combination. ....