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Study opens up new opportunities for controlling tuberculosis


Study opens up new opportunities for controlling tuberculosis
Boosting the body s own disease-fighting immune pathway could provide answers in the desperate search for new treatments for tuberculosis.
Tuberculosis still represents an enormous global disease burden and is one of the top 10 causes of death worldwide.
Led by WEHI s Dr Michael Stutz and Professor Marc Pellegrini and published in
Immunity, the study uncovered how cells infected with tuberculosis bacteria can die, and that using new medicines to enhance particular forms of cell death decreased the severity of the disease in a preclinical model.
At a glance
Researchers were able to demonstrate that cells infected with tuberculosis bacteria have functional apoptosis cell death pathways, and showed their importance in combatting severe disease. ....

Marc Pellegrini , Michael Stutz , Emily Henderson , Charles Viertel Charitable Foundation , National Health , Harry Secomb , Research Council , Professor Marc Pellegrini , Medical Research Council , Harry Secomb Trust , மார்க் பெலெக்ரீநீ , மைக்கேல் ஸ்டட்ஸ் , எமிலி ஹென்டர்சன் , தேசிய ஆரோக்கியம் , ஆராய்ச்சி சபை , ப்ரொஃபெஸர் மார்க் பெலெக்ரீநீ , மருத்துவ ஆராய்ச்சி சபை ,

Nanobodies inhibit SARS-CoV-2 infection


Date Time
Nanobodies inhibit SARS-CoV-2 infection
Australian researchers have identified neutralising nanobodies that block the SARS-CoV-2 virus from entering cells in preclinical models.
The discovery paves the way for further investigations into nanobody-based treatments for COVID-19.
Visualisation of SARS-CoV-2 virus with nanobodies (purple)
attaching to the virus ‘spike’ protein.
Image: Dr Drew Berry in collaboration with
Associate Professor Wai-Hong Tham
Published in PNAS, the research is part of a consortium-led effort, bringing together the expertise of Australian academic leaders in infectious diseases and antibody therapeutics at WEHI, the Doherty Institute and the Kirby Institute.
At a glance
Researchers have identified nanobodies that effectively blocked the SARS-CoV-2 virus from entering cells in pre-clinical models of COVID-19 infection. ....

Marcel Doerflinger , Alisa Glukhova , Matthew Oneill , Melanieh Dietrich , Amy Adair , Phillip Pymm , Hariprasad Venugopal , Michael Dengler , Marc Pellegrini , James Cooney , Cody Allison , Li Jin Chan , Doherty Institute , Kirby Institute , Research Future Fund , Monash Ramaciotti Centre For Cryo , Hengyi Group , Professor Wai Hong Tham , Associate Professor Wai Hong Tham , Professor Tham , Monash Ramaciotti Centre , Cryo Electron Microscopy , Senior Microscopist , Medical Research Future Fund , Matthewo Neill , Damien Drew ,

Explainer: Popular covid vaccine questions answered

Explainer: Popular covid vaccine questions answered
citynews.com.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from citynews.com.au Daily Mail and Mail on Sunday newspapers.

South Africa , United Kingdom , South African , Oxford Astrazeneca , Marc Pellegrini , ஒன்றுபட்டது கிஂக்டம் , மார்க் பெலெக்ரீநீ ,