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Date Time Nanobodies inhibit SARS-CoV-2 infection Australian researchers have identified neutralising nanobodies that block the SARS-CoV-2 virus from entering cells in preclinical models. The discovery paves the way for further investigations into nanobody-based treatments for COVID-19. Visualisation of SARS-CoV-2 virus with nanobodies (purple) attaching to the virus ‘spike’ protein. Image: Dr Drew Berry in collaboration with Associate Professor Wai-Hong Tham Published in PNAS, the research is part of a consortium-led effort, bringing together the expertise of Australian academic leaders in infectious diseases and antibody therapeutics at WEHI, the Doherty Institute and the Kirby Institute. At a glance Researchers have identified nanobodies that effectively blocked the SARS-CoV-2 virus from entering cells in pre-clinical models of COVID-19 infection. ....