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This brain circuit signals when to stop eating; could regulating it help with obesity

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Like a good story, feeding has a beginning, a middle and an end. It begins with appetite prompting the search for food, continues with eating the food and it ends when satiation hits and the consumption of food is stopped.
At Baylor College of Medicine, Dr. Qi Wu, Dr. Yong Han and their colleagues have uncovered new aspects of the last part of this story that relate to the little-known neural circuits and neurotransmitters involved in ending food consumption.
The team discovered a novel circuit that connects a unique subset of dopamine-producing neurons with downstream neurons in the hindbrain (lower brainstem) and potently suppresses food intake by triggering satiation in mice. They also found that the FDA-approved drug methylphenidate (MPH) mediates its noticeable weight loss effect by activating this particular circuit, opening the possibility that regulating this circuit might help people control weight. The study appears in the journal ....

United States , South Korea , Yong Xu , Kyong Han , Monica Farias , Qi Wu , Guobin Xia , American Heart Association , Pew Charitable , Sciences Advances , American Diabetes Association , Pew Scholarship Of Biomedical Sciences , Baylor Collaborative Faculty Research Investment Program , Centers Of Biomedical Research Excellence , Digestive Diseases Center , College Of Medicine , Baylor College Of Medicine , Baylor College , Shared Instrumentation , Diseases Center , Pew Charitable Trust , Faculty Start Up , Biomedical Research Excellence , Pew Scholarship , Biomedical Sciences , ஒன்றுபட்டது மாநிலங்களில் ,

Can regulating a novel brain circuit help control obesity?

Like a good story, feeding has a beginning, a middle and an end. It begins with appetite prompting the search for food, continues with eating the food. ....

United States , South Korea , Yong Xu , Kyong Han , Monica Farias , Qi Wu , Guobin Xia , American Heart Association , Pew Charitable , Sciences Advances , American Diabetes Association , Pew Scholarship Of Biomedical Sciences , Baylor Collaborative Faculty Research Investment Program , Centers Of Biomedical Research Excellence , Digestive Diseases Center , Baylor College Of Medicine , Baylor College , Shared Instrumentation , Diseases Center , Pew Charitable Trust , Faculty Start Up , Biomedical Research Excellence , Pew Scholarship , Biomedical Sciences , Brain Activity , Heart Disease ,

Researchers observe decision making in brain - and influence outcomes

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Researchers observe decision making in brain – and influence outcomes
A team of neuroscientists and engineers have developed a system that can show the neural process of decision making in real time, including the mental process of flipping between options before expressing a final choice.
By Taylor Kubota
In the course of deciding whether to keep reading this article, you may change your mind several times. While your final choice will be obvious to an observer – you’ll continue to scroll and read, or you’ll click on another article – any internal deliberations you had along the way will most likely be inscrutable to anyone but you. That clandestine hesitation is the focus of research, published Jan. 20 in Nature, by Stanford University researchers who study how cognitive deliberations are reflected in neural activity. ....

Stanford University , United States , Palo Alto , William Newsome , Hong Seh , Stepheni Ryu , Sania Fong , Roozbeh Kiani , Julian Brown , Paul Nuyujukian , Diogo Peixoto , Krishna Shenoy , Jessica Verhein , Jonathanc Kao , Los Angeles , Chand Chandrasekaran , Stanford Bio , Taylor Kubota , University Of California , Wu Tsai Neurosciences Institute , National Science Foundation , York University , Palo Alto Medical Foundation , National Institute Of Neurological Disorders , Office Of Naval Research , National Institutes Of Health ,