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El aviso de unos padres cuyo hijo falleció por un neuroblastoma

Reggie Hayes, un niño de solo cuatro años, falleció tras una dura batalla contra el neuroblastoma. Sus padres luchan por crear conciencia sobre este tipo de tumor. ....

Reggie Hayes , Joanne Hedley , Peter Hayes , Years Reggie Hayes , Clinic May , ரெகி வைக்கோல் , பீட்டர் வைக்கோல் ,

Researchers discover possible origin of neuroblastoma in the adrenal glands


Researchers discover possible origin of neuroblastoma in the adrenal glands
Neuroblastoma is a childhood cancer, most commonly affecting children aged between 2 -3 and can be fatal. Since the tumor cells resemble certain cells in the adrenal glands, a joint research group from MedUni Vienna s Center for Brain Research and the Swedish Karolinska Institute investigated the cellular origin of these cells and sympathetic neurons during the embryonic development of human adrenal glands. During the course of their investigations, they discovered a previously unknown cell type that might potentially be the origin of the tumor cells.
Treatments for this disease are extremely aggressive and challenging and relapses are not uncommon. So far, little is known about the origins of this cancer or the causes of relapse. However, it is assumed that neuroblastomas are due to abnormalities in the neural crest cells, which form the peripheral nervous system during embryogenesis. ....

Igor Adameyko , Emily Henderson , Swedish Karolinska Institute , Brain Research , Meduni Vienna Center , Meduni Vienna , Embryonic Development , எமிலி ஹென்டர்சன் , மூளை ஆராய்ச்சி ,

Combination of tumor cell vaccine and checkpoint therapy creates effective immune response


Combination of tumor cell vaccine and checkpoint therapy creates effective immune response
A personalized tumor cell vaccine strategy targeting Myc oncogenes combined with checkpoint therapy creates an effective immune response that bypasses antigen selection and immune privilege, according to a pre-clinical study for neuroblastoma and melanoma. The neuroblastoma model showed a 75% cure with long-term survival, researchers at Children s National Hospital found.
Myc is a family of regulator genes and proto-oncogenes that help manage cell growth and differentiation in the body. When Myc mutates to an oncogene, it can promote cancer cell growth. The Myc oncogenes are deregulated in 70% of all human cancers. ....

Xiaofang Wu , Emily Henderson , Sheikh Zayed Institute For Pediatric Surgical Innovation , Children National Hospital , National Hospital , Sheikh Zayed Institute , Pediatric Surgical Innovation , Immune Response , எமிலி ஹென்டர்சன் , ஷேக் ஸேயெட் நிறுவனம் க்கு குழந்தை அறுவை சிகிச்சை கண்டுபிடிப்பு , குழந்தைகள் தேசிய மருத்துவமனை , தேசிய மருத்துவமனை , ஷேக் ஸேயெட் நிறுவனம் , குழந்தை அறுவை சிகிச்சை கண்டுபிடிப்பு , நோய் எதிர்ப்பு சக்தி பதில் ,

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology


ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology
Alex s Lemonade Stand Foundation (ALSF), a nonprofit foundation devoted to finding cures for all children with cancer, announces grant award recipients of their Crazy 8 Initiative. The recipients will receive grants totaling more than $18.5 million, which is the single, largest funding commitment from ALSF to date.
The Initiative kicked off in the Fall of 2018 with a meeting that brought together more than 90 scientists from around the world to help define the research landscape in eight key areas of need in order to tackle major obstacles impeding progress toward cures for childhood cancer. Through a rigorous review process, ALSF received over 100 letters of intent from researchers that resulted in 83 full grant applications which were ultimately narrowed down to four projects that will work to accelerate the pace of new cure discovery. ....

United States , Seychelle Vos , Yaelp Moss , Jefferym Klco , Leonard Zon , Ross Levine , Emily Henderson , Klimenta Verba , Liz Scott , Zoran Rankovic , Peter Campbell , Igor Adameyko , Martin Eilers , Matthias Farlik , Martin Distel , Scotta Armstrong , Paula Northcott , Fernando Camargo , John Maris , Natalia Jura , Gwenn Hansen , Florian Halbritter , Charlesg Mullighan , Williama Weiss , M Madan Babu , Juerg Schwaller ,