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Sagimet Biosciences Appoints Life Sciences Industry Veteran Elizabeth Grammer to Board of Directors


Sagimet Biosciences Appoints Life Sciences Industry Veteran Elizabeth Grammer to Board of Directors
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SAN MATEO, Calif., May 3, 2021 /PRNewswire/  Sagimet Biosciences, a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today the appointment of Elizabeth Grammer, Esq., to its board of directors. Ms. Grammer brings to her role as director over 25 years of experience advising privately held and publicly traded life sciences companies at all stages of development.
George Kemble, Ph.D., Sagimet s chief executive officer, said,  Elizabeth is a strategic and innovative thinker with a passion for developing, articulating and leading the execution of corporate strategy and will be a great addition to our board. We look forward to leveraging her extensive experience to help Sagimet grow our business. ....

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Sagimet Biosciences Receives Fast Track Designation from U.S. Food and Drug Administration for FASN Inhibitor TVB-2640 in NASH


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SAN MATEO, Calif., March 16, 2021 /PRNewswire/ Sagimet Biosciences Inc., a clinical-stage biotechnology company focused on developing a portfolio of internally-discovered, selective fatty acid synthase (FASN) inhibitors, announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to TVB-2640 for the treatment of patients with NASH.
TVB-2640, is a wholly-owned, oral, selective inhibitor of FASN, a key enzyme involved in the production of saturated fatty acids in the liver and other organs, and is the only enzyme in the human body capable of converting metabolized sugars into palmitate.  In patients with NASH, increased FASN-mediated palmitate synthesis in the liver is the source of three key drivers of the disease: excess accumulation of liver fat, inflammation and fibrosis. ....

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Ascletis Joins Sagimet's US$80 Million in Crossover Financing with Premium Investors


Ascletis Joins Sagimet s US$80 Million in Crossover Financing with Premium Investors
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HANGZHOU, China and SHAOXING, China, Feb. 11, 2021 /PRNewswire/ Ascletis Pharma Inc. (HKEX: 1672) announces today that Ascletis, through its wholly-owned subsidiary, participates in Sagimet Biosciences Inc. s US$80 million in crossover financing, led by an undisclosed public equity healthcare investment fund with participation from other existing investors (Kleiner Perkins, New Enterprise Associates (NEA) and Rock Springs), along with new investors (Altium, HM Capital, Invus and PFM) (Details referring to Sagimet Biosciences press release: https://www.sagimet.com/press-releases/).
Prior to this crossover financing, Ascletis led a US$25 million Series E financing of Sagimet Biosciences in 2019. In conjunction with leading the Series E financing, Ascletis obtained an exclusive license from Sagimet Biosciences to develop, ....

United States , Hong Kong , Jinzij Wu , Sagimet Biosciences , Sagimet Bioscience , George Kemble , Kleiner Perkins , Sagimet Biosciences Inc , Enterprise Associates , Hong Kong Stock Exchange , Ascletis Pharma Inc , Prnewswire Ascletis Pharma Inc , New Enterprise Associates , Rock Springs , Greater China , Sagimet Chief Executive Officer , ஒன்றுபட்டது மாநிலங்களில் , ஹாங் காங் , ஜார்ஜ் கெஂபல் , கிளீனர் பெர்கின்ஸ் , நிறுவன கூட்டாளிகள் , ஹாங் காங் ஸ்டாக் பரிமாற்றம் , புதியது நிறுவன கூட்டாளிகள் , பாறை நீரூற்றுகள் , அதிகமானது சீனா ,