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Covid-19 Cases in US May Exceed 200K in the Next Few Weeks

Covid-19 cases in the US could exceed 200,000 a day due to the surge of the virus driven by the Delta variant. Nearly 4.3 million children had tested positive for Covid-19 in the country as of Aug. 5 since the onset of the pandemic. ....

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Protein as New Therapeutic Target for COVID-19

Galectin-3-binding protein (LGALS3BP) could be a new therapeutic anti-viral target for treating COVID-19. ....

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Rapid Antibody Testing For COVID-19

Rapid Antibody Testing For COVID-19
by Pooja Shete on
January 11, 2021 at 12:43 PM
An advanced nanomaterial-based biosensing platform has been found by the researchers that detects antibodies specific to SARS-CoV-2, the virus responsible for the COVID-19 pandemic within seconds. Additional to testing, this platform will help to quantify patient immunological response to the new vaccines with precision.
The study conducted by researchers at Carnegie Mellon University in collaboration with University of Pittsburgh (Pitt) and the UPMC is published in the journal
Advanced Materials.
The testing platform identified the presence of two virus antibodies- spike S1 protein and receptor binding domain (RBD), in a very small drop of blood. Antibody concentrations can also be detected in low concentrations and this detection happens through an electrochemical reaction within a handheld microfluidic device which sends results almost immediately to ....

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Spike Protein of COVID-19 Virus Reveals It's Mechanism

by Karishma Abhishek on
December 22, 2020 at 10:51 PM
COVID-19 causing coronaviruses have protein spikes on their surfaces that help the virus bind with the host receptors cells - first step of infection. Scientists have decoded the first detailed images of those spikes in their natural state, while still attached to the virus using cryogenic electron microscopy (cryo-EM) and computation techniques as per a study published in the journal
Quarterly Reviews Biophysics Discovery.
This serves as the critical step in designing therapeutic drugs and vaccines against the virus.
The advantage of doing it this way is that when you purify a spike protein and study it in isolation, you lose important biological context: How does it look in an intact virus particle? It could possibly have a different structure there, says Wah Chiu, a professor at DOE s SLAC National Accelerator Laboratory and Stanford University and senior author of the stu ....

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