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HMGA1 plays role in gastric cancer cell proliferation and metastasis

Aging-US published "HMGA1 promotes gastric cancer growth and metastasis by transactivating SUZ12 and CCDC43 expression" which reported that HMGA1 is overexpressed in GC cells and the high expression of HMGA1 was correlated with worse survival in GC patients using a bioinformatics assay. ....

Weimei Tang , Jide Wang , Li Xiang , Emily Henderson , Research Output , Xiang Wang Liu Tang Research Team , Side Liu , Tang Research Team , Gastric Cancer , Cell Proliferation , Fluorescence Imaging , N Vivo , லி கிஷியாங் , எமிலி ஹென்டர்சன் , ஆராய்ச்சி ஔட்‌புட் ,

Researchers identify genes associated with biochemical recurrence in prostate adenocarcinoma

Aging-US published "Identification of microenvironment related potential biomarkers of biochemical recurrence at 3 years after prostatectomy in prostate adenocarcinoma" which reported that the authors aimed to identify the potential prognostic genes in the prostate adenocarcinoma microenvironment and to estimate the causal effects simultaneously. ....

Fuzhong Xue , Emily Henderson , Shandong University , Research Output , Xue Research Team , Ene Expression , Prostate Cancer , எமிலி ஹென்டர்சன் , சாண்டோங் பல்கலைக்கழகம் , ஆராய்ச்சி ஔட்‌புட் ,

Oncotarget: Modulating Tau Post-translational modifications and cytoskeletal network


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IMAGE: EGCG maintains neuronal cell cytoskeleton integrity. Methyl glyoxal treatment leads to glycation of actin and microtubules leading to hampered growth of neuritic extensions and microtubule organization. Microtubule stabilization by +TIP.
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Credit: Correspondence to - Subashchandrabose Chinnathambi - [email protected]
Epigallocatechin-3-gallate modulates Tau Post-translational modifications and cytoskeletal network which reported that the chemical modulators of Tau PTMs, such as kinase inhibitors and antibody-based therapeutics, have been developed, but natural compounds, as modulators of Tau PTMs are not much explored.
These authors applied biophysical and biochemical techniques like fluorescence kinetics, oligomerization analysis and transmission electron microscopy to investigate the impact of EGCG on Tau glycation ....

Subashchandrabose Chinnathambi , Innovative Research , Chinnathambi Research Team , Impact Journals , Research Output , Academy Of Scientific , Chemical Laboratory , Tau Post Translational , National Chemical Laboratory , புதுமையானது ஆராய்ச்சி , ஒலி கிளவுட் , தாக்கம் பத்திரிகைகள் , ஆராய்ச்சி ஔட்‌புட் , கலைக்கழகம் ஆஃப் அறிவியல் , இரசாயன ஆய்வகம் , தேசிய இரசாயன ஆய்வகம் ,