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Novel approach to interrogate tissue-specific protein-protein interactions

Multicellular organisms, like animals and plants, have complex cells with diverse functions. This complexity arises from the need for cells to produce distinct proteins that interact with each other. This interaction is crucial for cells to carry out their specific tasks and to form complex molecular machinery. However, our current understanding of such protein-protein interactions often lacks cellular contexts because they were usually studied in an in vitro system or in cells isolated from their tissue environment. Effective methods to investigate protein-protein interactions in a tissue-specific manner are largely missing. ....

Xiang David Li , Li Ka Shing , Xiang David , Chaogu Zheng , School Of Biomedical Sciences , Proceedings Of The National Academy Sciences , Department Of Chemistry , School Of Biological Sciences , University Of Hong Kong , Hong Kong , Professor Xiang David , Professor Chaogu , Biological Sciences , Biomedical Sciences , Methionine Analog Based Cell Specific Proteomics , National Academy ,

Histone Mark Decoded: Key to Gene Regulation in Cancer

Histone Mark Decoded: Key to Gene Regulation in Cancer
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Xiang David Li , Xiang David , Yuanliang Zh , School Of Biological Sciences , Department Of Chemistry , School Of Biomedical Sciences , University Of Hong Kong , Professor Xiang David , Hong Kong , Biological Sciences , Biomedical Sciences ,