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Key Barriers in Implementing Guideline-Directed Cholesterol Treatment

Clinical pharmacists discuss how to address key barriers that get in the way of implementing guideline-directed cholesterol treatment. ....

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Stricter LDL-C Targets: Explaining Goalpost Changes to Patients

Key opinion leaders in cardiology share insights on reducing LDL cholesterol to manage cardiovascular disease risk, educating patients not reaching goals, and implementing real-world clinical strategies for maintaining lower LDL levels. ....

Explaining Goalpost Changes , Vldl Cholesterol , Low Density Lipoprotein , Bad Cholesterol , Cholesterol Levels , Cardiovascular Health , Heart Disease Risk , Plaque Buildup , Lipid Profile , Cholesterol Management ,

Extended Zerlasiran Data Show Sustained Lp(a) Reduction

The experimental siRNA agent led to prolonged Lp(a) reduction of more than 90%, extended data from the phase 1 trial show, supporting the move to phases 2 and 3 trials. ....

New York , United States , Stevene Nissen , Roberts Rosenson , Icahn School Of Medicine At Mount Sinai , Cleveland Clinic , Silence Therapeutics , Icahn School , Mount Sinai , New York City , Ipid Management , Vldl Cholesterol , Low Density Lipoprotein Cholesterol , Atherosclerotic Heart Disease , Therosclerotic Cardiovascular Disease , Oronary Heart Disease , Schemic Heart Disease , Coronary Artery Disease , Cardiovascular Disease , Vd Cardiovascular Disease , Clinical Research , Clinical Trials , Linical Studies , Pre Clinical Trial , Double Blind Study , Double Blind Studies ,

Early Olezarsen Results Show 50% Reduction in Triglycerides

A drug targeting mRNA essential for APO C-III production provided a 50% reduction in triglycerides in BRIDGE-TIMI 73a, the largest ever observed in a controlled trial. ....

United States , North Carolina , Daniel Soffer , Brian Bergmark , Nehaj Pagidipati , National Lipid Association , American College Of Cardiology , Duke Clinical Research Institute , Duke School Of Medicine , American College , Scientific Session , New England , Major Subgroup Failed , North America , Penn Medicine , National Lipid , Duke School , Ipid Management , Cv Risk , Cardiovascular Risk , V Risk Factors , Cardiovascular Risk Factors , Cardiovascular Risk Management , Hypertriglyceridemia Hypertriglyceridaemia , Liver Enzymes , Liver Studies ,

Gene Editing Experiment Halted as Patient Gets Weird Side Effects

The experimental biotech startup Verve Therapeutics has paused the first phase of a buzzy human gene-editing trial due to strange side effects in a patient, according to a report from Bloomberg. The trial in question — dubbed the "Heart-1" trial — is the company's attempt to use gene editing to reduce heart-attack-causing cholesterol in patients […] ....

Verve Therapeutics , Heart Attack , Vldl Cholesterol , Verve Therapeutics , Familial Hypercholesterolemia , Gene Editing , Side Effects , Trial Participants , Human Trial ,