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Two siRNA Therapeutics Safely Lower Triglycerides in Mixed Hyperlipidemia

Two siRNA Therapeutics Safely Lower Triglycerides in Mixed Hyperlipidemia
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United States , New York , Baylor College Of Medicine , Pradeep Natarajan , Brian Bergmark , Robert Rosenson , Christie Ballantyne , Md Baylor College Of Medicine , Ionis Pharmaceuticals , Arrowhead Pharmaceuticals , European Atherosclerosis Society , Kowa Pharmaceuticals , New England Journal , Baylor College , Icahn School , Mount Sinai , Massachusetts General Hospital ,

New Drug Cuts Blood Triglyceride Levels in Half

New Drug Cuts Blood Triglyceride Levels in Half
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Brian Bergmark , American College Of Cardiology , Women Hospital Division Of Cardiovascular Medicine , Harvard Medical School , New England Journal , American College , Hospital Division , Harvard Medical ,

Triglyceride-Lowering Therapies Provide Favorable Outcomes in Early Testing

In Bridge-TIMI 73a and SHASTA-2, the RNA-silencing therapies cut triglycerides quickly, offering hope for hard-to-treat patients. ....

University Of Pennsylvania , United States , Western Australia , Daniel Soffer , Brian Bergmark , Daniel Gaudet , Gerald Watts , Neha Pagidipati , Pradeep Natarajan , Phd University Of Western Australia , Phd University Of Montreal , Md Duke University School Of Medicine , Ionis Pharmaceuticals , Md University Of Pennsylvania School Medicine , Arrowhead Pharmaceuticals , Drug Administration , American College Of Cardiology , American College , Pennsylvania School , Duke University School , New England Journal , Massachusetts General Hospital ,

New Drug Could Slash Blood Triglyceride Levels

New Drug Could Slash Blood Triglyceride Levels
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Early Olezarsen Results Show 50% Reduction in Triglycerides

A drug targeting mRNA essential for APO C-III production provided a 50% reduction in triglycerides in BRIDGE-TIMI 73a, the largest ever observed in a controlled trial. ....

United States , North Carolina , Daniel Soffer , Brian Bergmark , Nehaj Pagidipati , National Lipid Association , American College Of Cardiology , Duke Clinical Research Institute , Duke School Of Medicine , American College , Scientific Session , New England , Major Subgroup Failed , North America , Penn Medicine , National Lipid , Duke School , Ipid Management , Cv Risk , Cardiovascular Risk , V Risk Factors , Cardiovascular Risk Factors , Cardiovascular Risk Management , Hypertriglyceridemia Hypertriglyceridaemia , Liver Enzymes , Liver Studies ,