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Seladelpar normalizes ALP, reduces pruritis vs placebo in primary biliary cholangitis

Seladelpar normalizes ALP, reduces pruritis vs placebo in primary biliary cholangitis
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Gideonm hirschfieldTerry hornerHeather bieleBykate burbaUniversity of torontoTerry horner chairAutoimmune liver diseaseNew england journal

Genuinely exciting phase 3 results for CymaBay s seladelpar

Results from a phase 3 trial looking at treatment for primary biliary cholangitis (PBC) are 'genuinely exciting' and support the potential for seladelpar to raise the bar in treatment of the disease.

Charles mcwherterTerry hornerCymabay therapeutics incToronto centre for liver diseaseCymabay therapeuticsNew england journalGideon hirschfieldTerry horner chairToronto centreNew drug application

RESPONSE: Seladelpar Normalizes Alkaline Phosphatase, Reduces Pruritus in PBC

Results from the phase 3 trial showed seladelpar elicited biochemical response, normalized alkaline phosphatase, and reduced pruritus at a greater rate than placebo.

David assisTerry hornerGideon hirschfieldYale school of medicineAutoimmune liver disease researchDrug administrationUniversity of torontoFoundation gideon hirschfieldNew england journalYale schoolCymabay therapeutic new drug applicationPriority reviewPrescription drug user fee actTerry horner chairPrimary biliaryImproves markers

The New England Journal of Medicine Publishes Positive Phase 3 RESPONSE Data of CymaBay s Seladelpar in Primary Biliary Cholangitis

The New England Journal of Medicine Publishes Positive Phase 3 RESPONSE Data of CymaBay s Seladelpar in Primary Biliary Cholangitis
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Arran attridgeTheresa dolgeTerry hornerGideon hirschfieldCharles mcwherterCymabay therapeutics incToronto centre for liver diseaseAutoimmune liver disease researchRegulatory agencyLifesci advisorsDrug administrationExchange commissionPrnewswire cymabay therapeutics incEuropean medicines agencyBay therapeuticsNew england journal

Scott A Horner

Williamsport, Pa. — Scott A. Horner, 48, most recently of Williamsport, died Monday, Jan. 29, 2024.

Scott hornerTerry horner angieTiffany georgeScotta hornerViolete hornerBrenna horner zach woodcockAlan ray hornerNancyk hainesAvonlea millerJanice louise haines hornerJennie houser michaelKaty ortesKaitlyn hornerJanice louiseBrenna hornerZach woodcock