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MiRNA-mRNA regulatory network and potential causative agents

During asthma progression, the intricate molecular networks, including microRNA transcriptional regulation in airway epithelium, remain largely undefined. ....

United States , Boster Biological Technology , Rnas In Airway Remodeling , Gene Ontology , Kyoto Encyclopedia , Gene Expression Omnibus , Operating Characteristic , Pathway Enrichment Analyses , Integrated Discovery , Dual Luciferase Reporter Assay , Target Gene , Predicted Target , Eosinophilic Inflammation Cellular , Affected Airway Remodeling ,

[Full text] LINC00184 promotes OC proliferation and cisplatin resistance

Yuwen Han, Jun You, Yun Han, Yinglei Liu, Menghui Huang, Xiaoyan Lu, Jingjing Chen, Yanli Zheng
Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu Province, People’s Republic of China
Correspondence: Yanli Zheng
Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Nantong University, No. 6 North Hai-Er-Xiang Road, Chongchuan District, Nantong, 226001, Jiangsu Province, People’s Republic of China
Tel +86-0513-85061000
Objective: Cisplatin resistance is one of the main reasons for treatment failure in ovarian cancer (OC). Here, the effects of LINC00184 on cisplatin-resistant OC were studied.
Patients and Methods: LINC00184, miR-1305 and CNTN1 expression in tissues from 70 OC patients was determined by qRT-PCR, in situ hybridization and Western blot. OC cell lines and OC cisplatin-resistant cell lines were cultured. Cells were transfected using Lipofectamine 2000 an ....

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[Full text] LncRNA SNHG8 Serves as an Oncogene in Breast Cancer Through miR-634/ZB

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1Key Laboratory of Prevention and treatment of cardiovascular and cerebrovascular diseases of Ministry of Education, Jiangxi Provincial Clinical Research Center for Vascular Anomalies, Basic Medical School, Gannan Medical University, Ganzhou, Jiangxi, 341000, People’s Republic of China;
2Basic Medical School, Gannan Medical University, Ganzhou, Jiangxi, 341000, People’s Republic of China;
3Department of Pediatric Surgery, Jiangxi Provincial Clinical Research Center for Vascular Anomalies, Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases of Ministry of Education, The First Affiliate Hospital of Gannan Medical University, Ganzhou, Jiangxi, 341000, People’s Republic of China
These authors contributed equally to this work
Correspondence: Qian Liu ....

United States , United Kingdom , Eteläuomen Läi , Transwell Chamber Assay , Biosystems Inc , Shanghai Institute Of Biochemistry , Spss Inc , Hospital Of Gannan Medical University , Chinese Academy Of Sciences , World Medical Association Declaration Of Helsinki , Ethics Committee , Medical Ethics Committee , Gannan Medical , World Medical Association Declaration , Chinese Academy , Shanghai Institute , Cell Biology , Forma Scientific United Kingdom , Applied Biosystems , Santa Cruz , Synthgene Biotech , Dual Luciferase Reporter Assay , Breast Cancer Cells Proliferation , While Accelerating , Target Gene , Breast Cancer ,