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Why All Your Love is Unrequited (and What to Do About It) lifehacker.com.au - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from lifehacker.com.au Daily Mail and Mail on Sunday newspapers.
“Plan A” is an emotional gut-punch that will linger in your heart, and soul after the end credits have finished and asks serious questions about revenge. ....
Date Time Researchers Demonstrate How Defects in Mitochondria May Lead to Autism Spectrum Disorder Researchers at Children’s Hospital of Philadelphia (CHOP) have demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells. The findings were published online by the Proceedings of the National Academy of Sciences. Multiple studies have revealed hundreds of mutations associated with autism spectrum disorder, but there is no consensus as to how these genetic changes cause the condition. Biochemical and physiological analyses have suggested that deficiencies in mitochondria, the “batteries” of the cell that produce most of the body’s energy, might be a possible cause. Recent studies have shown that variants of mitochondrial DNA (mtDNA) are associated with autism spectrum disorder. ....
Autism Link to Mitochondrial Defects May Enable Future Metabolic Therapies February 2, 2021 Research in mice by scientists at Children’s Hospital of Philadelphia (CHOP) has demonstrated that autism spectrum disorder (ASD) may be caused by defects in the mitochondria of brain cells. Their findings point to the potential to develop metabolic therapies as a potential treatment strategy for at least some ASD patients. “Our study shows that mild systemic mitochondrial defects can result in autism spectrum disorder without causing apparent neuroanatomical defects,” noted Douglas C. Wallace, PhD, director of the Center for Mitochondrial and Epigenomic Medicine and the Michael and Charles Barnett endowed chair in pediatric mitochondrial medicine and metabolic diseases at CHOP. “These mutations appear to cause tissue-specific brain defects. While our findings warrant further study, there is reason to believe that this could lead to better diagnosis of autism and potentiall ....