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B cells drive responses of other immune cells, and can be modified to prevent Multiple Sclerosis symptoms

B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), challenging the prevailing view that T cells are the principle orchestrators of immune responses. In individuals with Multiple Sclerosis (MS), abnormally active respiration in B cells drives pro-inflammatory responses of myeloid cells and T cells, leading them to attack the protective sheath (myelin) that covers nerve fibers, and leading to nerve damage that causes symptoms of MS. ....

United States , University Of Pennsylvania , National Institutes Of Health Autoimmunity Center , Perelman School Of Medicine , Science Foundation Of China , National Natural , Penn Center , Paul Anderson Gift Fund , Perelman School , Amit Bar Or , National Institutes , Health Autoimmunity Center , Epigenomic Medicine , Science Foundation ,

Mitochondrial Dysfunction & Chronic Fatigue: Takeaways & Prevention

Mitochondrial Dysfunction & Chronic Fatigue: Takeaways & Prevention
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B Cells Drive Responses Of Other Immune Cells

B Cells Drive Responses Of Other Immune Cells
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United States , University Of Pennsylvania , National Institutes Of Health Autoimmunity Center , Perelman School Of Medicine , Paul Anderson Gift Fund , Penn Center , Science Foundation Of China , National Natural , Multiple Sclerosis , Perelman School , Amit Bar Or , National Institutes , Health Autoimmunity Center , Epigenomic Medicine , Science Foundation ,

COVID causes mitochondrial dysfunction in multiple organs

The genes of the mitochondria, the energy producers of our cells, can be negatively impacted by SARS-CoV-2, leading to dysfunction in multiple organs beyond the lungs. ....

United States , Douglasc Wallace , Joseph Guarnieri , Afshin Beheshti , International Research Team , Research Team , Epigenomic Medicine , Science Translational , Covid 19 , Ars Cov 2 , Childrens Hospital Of Philadelphia , Ovid 19 International Research Team , Mitochondrial Dysfunction ,

COVID-19 causes mitochondrial dysfunction in heart and other organs, researchers find

COVID-19 causes mitochondrial dysfunction in heart and other organs, researchers find
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Afshin Beheshti , Douglasc Wallace , Joseph Guarnieri , Gates Foundation , Broad Institute , Division Of Intramural Research , Melinda Gates Foundation , Epigenomic Medicine , Intramural Research ,