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Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression

Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression
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IKKβ–NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice

IKKβ–NF-κB signaling in adult chondrocytes promotes the onset of age-related osteoarthritis in mice
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Transcranial magnetic stimulation in Alzheimer's Disease

Transcranial magnetic stimulation in Alzheimer's Disease
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Topical delivery of Levocarnitine for Dry Eye Disease

Discussion
New technologies have been explored in many researches such as a kind of long-acting mucoadhesive thermogels and gallate-loaded gelatin-g-poly (N-Isopropylacrylamide) for the treatment of DED. As the first recommended drug in “Dry Eye Diagnosis and Treatment Guidelines”, the protective effect of LC on corneal epithelial cells under hypertonic state has been verified.
22–24 Another research group prepared an artificial formulation which also used LC as a part of formulation to help replenish the tear film.
25 In this study, a kind of thermosensitive in situ gel of LC was prepared which is in a floating condition at room temperature while can form a gel rapidly as soon as dropped in the ocular surface of rabbits. The mechanism of the gelatinization under specific temperature of LCTG was relevant with hydrophobic effect of groups, hydrogen-bond interaction among polymer chains and hydrogen-bond interaction among hydrophilic group. On the one hand, LCTG ca ....

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Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibito

Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen–Glucose Deprivation-Induced Ischemic Neuronal Injury ....

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