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Goldilocks Binding Strength Dictates T-cell Cancer Battle Outcome

Goldilocks Binding Strength Dictates T-cell Cancer Battle Outcome
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Mohamed nadhir djekidelDietmar zehnPartha chowdhuryShannon boiXueyan liuBenjamin youngbloodYongqiang fengUniversity of tennessee health science centerCollege of graduate health sciencesJude children research hospitalJude department of immunologyNational institutes of healthUniversity of new orleansTechnical university of munichJude childrenResearch hospital

Young vs old: How host environment affects immune response

Benjamin Youngblood, Ph.D., and Ardiana Moustaki, Ph.D., of the St. Jude Department of Immunology. Most clinical studies of the immune system use

Elizabeth stewartShannon boiAnthony zamoraMichael dyerScott newmanAlberto pappoScott foyAntonina silkovPaul thomasBen youngbloodNatalie mcdonaldSara federicoBenjamin youngbloodArdie moustakiArdiana moustakiNational cancer institute

Exhaustion affects CAR T-cell clinical response

L to R: Benjamin Youngblood, Ph.D.; Aimee Talleur, M.D.; Caitlin Zebley, M.D., Ph.D.; and Stephen Gottschalk, M.D. St. Jude Children’s Research

Shannon boiBrandon triplettGiovanni gallettiAimee talleurCharmaine brownJean yves metaisDeanne langfittEnrico lugliBenjamin youngbloodCaitlin zebleyMichael meagherStephen gottschalkJude children research hospitalNational institutes of healthJude department of bone marrow transplantationLaboratory of translational immunology