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Goldilocks Binding Strength Dictates T-cell Cancer Battle Outcome

Goldilocks Binding Strength Dictates T-cell Cancer Battle Outcome
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Mohamed nadhir djekidelDietmar zehnPartha chowdhuryShannon boiXueyan liuBenjamin youngbloodYongqiang fengUniversity of tennessee health science centerCollege of graduate health sciencesJude children research hospitalJude department of immunologyNational institutes of healthUniversity of new orleansTechnical university of munichJude childrenResearch hospital

Combination therapy overcomes BET inhibitor resistance

Combination therapy overcomes BET inhibitor resistance
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United statesYang zhangMohamed nadhir djekidelJudith hyleJunj yangWojciech rosikiewiczPhong wangMarina konoplevaRui luShaela wrightSteven kornblauBeisi xuChunliang liGlenn hasseUniversity of alabama at birminghamAmerican cancer society

Pioneering approach advances study of CTCF protein in transcription biology

Pioneering approach advances study of CTCF protein in transcription biology
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Mohamed nadhir djekidelJustin williamsShaela wrightMasato kanemakiBeisi xuChunliang liJudith hyleYing shaoJude centerNational institute of geneticsJude children research hospitalJude department of tumor cell biologyJude childrenResearch hospitalGenome biologyNational institute

Scientists use next-generation protein degradation technology to study CTCF s role in transcription

CTCF is a critical protein known to play various roles in key biological processes such as transcription. Scientists at St. Jude Children's Research Hospital used a next-generation protein degradation technology to study CTCF.

Masato kanemakiMohamed nadhir djekidelChunliang liJudith hyleEmily hendersonJude centerNational institute of geneticsJude children research hospitalJude department of tumor cell biologyJude childrenResearch hospitalGenome biologyNational instituteCo corresponding authorJude departmentTumor cell