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Systemic sclerosis

Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue
disease. Once considered an untreatable and unpredictable condition, research advancements
have improved our understanding of its disease pathogenesis and clinical phenotypes
and expanded our treatment armamentarium. Early and accurate diagnosis is essential,
while ongoing efforts to risk stratify patients have a central role in predicting
both organ involvement and disease progression. A holistic approach is required when
choosing the optimal therapeutic strategy, balancing the side-effect profile with
efficacy and tailoring the treatment according to the goals of care of the patient. ....

Ma An , United States , United Kingdom , Sri Lanka , France General , J Clin Rheumatol , Respir Pulm , Semin Hematol , Almeida Chaves , Chemother Pharmacol , Coll Cardiol , Matucci Cerinic , Los Angeles , Clin Rheumatol , J Clin Gastroenterol , Acta Gastroenterol Latinoam , Medsger Jr , Scandj Gastroenterol , Scleroderma Intervention Network , Canadian Scleroderma Research Group , Scleroderma Clinical Trials Consortium Gastrointestinal Tract , International Scleroderma Renal Crisis Study , Eurj Health Econ , International Scleroderma Renal Crisis , Research Group , European Reference Network ,

Lockdown as the mother of invention: disruptive technology in a disrupted time

Comprehensive care for people with interstitial lung disease (ILD) requires careful
monitoring and attention to detail. Many of the details that are important to inform
best care in ILDs can now be monitored outside the clinic, thanks to advances in technology.
Such monitoring includes remote measurement of lung function, monitoring of symptoms
and treatment side-effects, and documentation of important health behaviours (such
as medication adherence and physical activity). Marlies Wijsenbeek and colleagues
provide a comprehensive overview of how these technologies have been applied in the
care of people with ILD,1 a topic of relevance to both research and clinical practice. ....

Marlies Wijsenbeek , Respir Rev ,

Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study

Balloon pulmonary angioplasty versus riociguat for the treatment of inoperable chronic thromboembolic pulmonary hypertension (RACE): a multicentre, phase 3, open-label, randomised controlled trial and ancillary follow-up study
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Clin Cardiol , Englj Med , Respir Med , Cardiovasc Interv , Cardiovasc Qual Outcomes , Respir Rev , Heart Lung Transplant ,

Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study

Association between very to moderate preterm births, lung function deficits, and COPD at age 53 years: analysis of a prospective cohort study
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Tasmanian Longitudinal Health Study , European Community Respiratory Health Survey , European Community Respiratory Health , Lancet Glob Health , Lancet Child Adolesc Health , Glob Health , Child Adolesc Health , Respir Med , Allergy Clin Immunol , Respir Rev , Chronic Obstructive Pulmonary , Englj Med , Chronic Obstructive Pulmonary Disease ,