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Systemic sclerosis

Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue
disease. Once considered an untreatable and unpredictable condition, research advancements
have improved our understanding of its disease pathogenesis and clinical phenotypes
and expanded our treatment armamentarium. Early and accurate diagnosis is essential,
while ongoing efforts to risk stratify patients have a central role in predicting
both organ involvement and disease progression. A holistic approach is required when
choosing the optimal therapeutic strategy, balancing the side-effect profile with
efficacy and tailoring the treatment according to the goals of care of the patient. ....

Ma An , United States , United Kingdom , Sri Lanka , France General , J Clin Rheumatol , Respir Pulm , Semin Hematol , Almeida Chaves , Chemother Pharmacol , Coll Cardiol , Matucci Cerinic , Los Angeles , Clin Rheumatol , J Clin Gastroenterol , Acta Gastroenterol Latinoam , Medsger Jr , Scandj Gastroenterol , Scleroderma Intervention Network , Canadian Scleroderma Research Group , Scleroderma Clinical Trials Consortium Gastrointestinal Tract , International Scleroderma Renal Crisis Study , Eurj Health Econ , International Scleroderma Renal Crisis , Research Group , European Reference Network ,