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Biliary tract cancers have increased in incidence in many parts of the world, particularly cases of intrahepatic disease.1,2 The incidence of cholangiocarcinoma varies geographically, with 1·6 cases per 100 000 people in the USA, for example, but substantially higher rates in parts of east Asia.2 Most patients present with advanced disease not amenable to surgery and require systemic therapy. For more than 10 years, gemcitabine and cisplatin was the internationally accepted first-line treatment for patients with locally advanced and metastatic biliary tract cancer, as per the ABC-02 study. ....
Combined advances in haematopoietic cell transplantation (HCT) and intensive care management have improved the survival of patients with haematological malignancies admitted to the intensive care unit. In cases of refractory respiratory failure or refractory cardiac failure, these advances have led to a renewed interest in advanced life support therapies, such as extracorporeal membrane oxygenation (ECMO), previously considered inappropriate for these patients due to their poor prognosis. Given the scarcity of evidence-based guidelines on the use of ECMO in patients receiving HCT and the need to provide equitable and sustainable access to ECMO, the European Society of Intensive Care Medicine, the Extracorporeal Life Support Organization, and the International ECMO Network aimed to develop an expert consensus statement on the use of ECMO in adult patients receiving HCT. ....
Aspirin and cancer survival: a systematic review and meta-analyses of 118 observational studies of aspirin and 18 cancers ecancer.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from ecancer.org Daily Mail and Mail on Sunday newspapers.
Camrelizumab plus carboplatin and pemetrexed versus chemotherapy alone in chemotherapy-naive patients with advanced non-squamous non-small-cell lung cancer (CameL): a randomised, open-label, multicentre, phase 3 trial thelancet.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from thelancet.com Daily Mail and Mail on Sunday newspapers.