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Faulty DNA disposal system found to cause inflammation

Faulty DNA disposal system found to cause inflammation
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Laura Newman , Gerald Shadel , Audrey Geisel , University Of Virginia , Salk Institute , San Diego Nathan Shock Center , Nature Cell Biology , Professor Gerald Shadel , Basic Biology , Audrey Geisel Chair , Biomedical Science ,

Faulty DNA disposal system causes inflammatio

<p>Salk scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.</p>
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Audrey Geisel , Joshua Chevez , Sagnika Ghosh , Matthew Donnelly , Nimesha Tadepalle , Jonas Salk , Gladys Rojas , Gerald Shadel , Laura Newman , Ricardo Rodriguez Enriquez , Danielle Grotjahn , Michaela Medina , Sammy Weiser Novak , Cara Schiavon , Ian Lemersal , Salk Institute , San Diego Nathan Shock Center , Jolla Institute For Immunology , Yale University School Of Medicine Center , Waitt Foundation , Initiative In Brain Health , Salk Pioneer Fund Postdoctoral Scholar Award , National Science Foundation Neuronex Award , Chan Zuckerberg Initiative Imaging Scientist Award , University Of Virginia , Scripps Research Institute ,

Inflammation Linked to Faulty DNA Disposal System

Inflammation Linked to Faulty DNA Disposal System
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Laura Newman , Cara Schiavon , Matthew Donnelly , Audrey Geisel , Ian Lemersal , Sammy Weiser Novak , Michaela Medina , Nimesha Tadepalle , Ricardo Rodriguez Enriquez , Jonas Salk , Gladys Rojas , Danielle Grotjahn , Sagnika Ghosh , Joshua Chevez , Gerald Shadel , Scripps Research Institute , Jolla Institute For Immunology , Initiative In Brain Health , University Of Victoria , University Of Virginia , National Institutes Of Health , Canada Research , Salk Pioneer Fund Postdoctoral Scholar Award , San Diego Nathan Shock Center , Salk Institute For Biological , Yale University School Of Medicine Center ,

Faulty DNA disposal system causes inflammation

Faulty DNA disposal system causes inflammation
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Ricardo Rodriguez Enriquez , Gerald Shadel , Audrey Geisel , Laura Newman , Michaela Medina , Danielle Grotjahn , Matthew Donnelly , Joshua Chevez , Sammy Weiser Novak , Cara Schiavon , Ian Lemersal , Sagnika Ghosh , Nimesha Tadepalle , Gladys Rojas , Salk Pioneer Fund Postdoctoral Scholar Award , Chan Zuckerberg Initiative Imaging Scientist Award , Yale University School Of Medicine Center , National Institutes Of Health , National Science Foundation Neuronex Award , Waitt Foundation , Scripps Research Institute , University Of Victoria , University Of Virginia , Jolla Institute For Immunology , Canada Research , Initiative In Brain Health ,

Faulty DNA disposal system causes inflammatio

Faulty DNA disposal system causes inflammatio
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Jonas Salk , Nimesha Tadepalle , Gladys Rojas , Laura Newman , Joshua Chevez , Danielle Grotjahn , Cara Schiavon , Audrey Geisel , Ian Lemersal , Sammy Weiser Novak , Matthew Donnelly , Gerald Shadel , Sagnika Ghosh , Ricardo Rodriguez Enriquez , Michaela Medina , National Science Foundation Neuronex Award , San Diego Nathan Shock Center , Salk Institute , Initiative In Brain Health , University Of Victoria , Jolla Institute For Immunology , Yale University School Of Medicine Center , Chan Zuckerberg Initiative Imaging Scientist Award , University Of Virginia , Salk Institute For Biological , National Institutes Of Health ,