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Faulty DNA disposal system found to cause inflammation

Faulty DNA disposal system found to cause inflammation
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Laura newmanGerald shadelAudrey geiselUniversity of virginiaSalk instituteSan diego nathan shock centerNature cell biologyProfessor gerald shadelBasic biologyAudrey geisel chairBiomedical science

Faulty DNA disposal system causes inflammatio

<p>Salk scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.</p>

Audrey geiselJoshua chevezSagnika ghoshMatthew donnellyNimesha tadepalleJonas salkGladys rojasGerald shadelLaura newmanRicardo rodriguez enriquezDanielle grotjahnMichaela medinaSammy weiser novakCara schiavonIan lemersalSalk institute

Inflammation Linked to Faulty DNA Disposal System

Inflammation Linked to Faulty DNA Disposal System
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

Laura newmanCara schiavonMatthew donnellyAudrey geiselIan lemersalSammy weiser novakMichaela medinaNimesha tadepalleRicardo rodriguez enriquezJonas salkGladys rojasDanielle grotjahnSagnika ghoshJoshua chevezGerald shadelScripps research institute

Faulty DNA disposal system causes inflammation

Faulty DNA disposal system causes inflammation
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Ricardo rodriguez enriquezGerald shadelAudrey geiselLaura newmanMichaela medinaDanielle grotjahnMatthew donnellyJoshua chevezSammy weiser novakCara schiavonIan lemersalSagnika ghoshNimesha tadepalleGladys rojasSalk pioneer fund postdoctoral scholar awardChan zuckerberg initiative imaging scientist award

Faulty DNA disposal system causes inflammatio

Faulty DNA disposal system causes inflammatio
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Jonas salkNimesha tadepalleGladys rojasLaura newmanJoshua chevezDanielle grotjahnCara schiavonAudrey geiselIan lemersalSammy weiser novakMatthew donnellyGerald shadelSagnika ghoshRicardo rodriguez enriquezMichaela medinaNational science foundation neuronex award