Cells in the human body contain power-generating mitochondria, each with their own mtDNA a unique set of genetic instructions entirely separate from the cell’s nuclear DNA that mitochondria use to create life-giving energy. When mtDNA remains where i
<p>Salk scientists discovered a pathway from mitochondrial DNA replication stress to immune system activation and inflammation, finding that endosomes responsible for disposing of dysfunctional mitochondrial DNA were leaking mitochondrial DNA into the cell and prompting the inflammatory immune response. The pathway provides new targets for therapeutics that disrupt inflammation during aging and disease.</p>
Inflammation Linked to Faulty DNA Disposal System miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.
Cells in the human body contain power-generating mitochondria, each with their own mtDNA-;a unique set of genetic instructions entirely separate from the cell's nuclear DNA that mitochondria use to create life-giving energy.
Faulty DNA disposal system causes inflammation sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.