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FDA approves supplemental new drug application for Rexulti

The FDA has approved a supplemental new drug application for Rexulti for the treatment of agitation associated with dementia due to Alzheimer’s disease.According to a joint press release from Otsuka and Lundbeck, the approval makes Rexulti (brexpiprazole, Otsuka/Lundbeck) the first and only treatment approved in the United States for this common neuropsychiatric symptom of AD, which is ....

United States , Otsuka Lundbeck , Heather Biele , Makoto Inoue , Deborah Dunsire , Cohen Mansfield Agitation ,

Vitamin D supplementation not tied to mental health outcomes in first-episode psychosis

Vitamin D supplementation did not appear linked to mental health or metabolic outcomes at 6 months in people with first-episode psychosis, according to results of a randomized clinical trial published in JAMA Network Open. “We report the results of the DFEND (Vitamin D Supplementation Compared to Placebo in People With First Episode Psychosis–Neuroprotection Design) trial,” ....

Otsuka Lundbeck ,