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Center for Contemporary Sciences (CCS) Partners with BICO to Modernize Medical Research and Drug Development

/PRNewswire/ Today, the Center for Contemporary Sciences (CCS) and BICO formalized a strategic partnership aiming at modernizing drug development and. ....

United States , Erik Gatenholm , Aysha Akhtar , Contemporary Sciences , Cosmetics Act , Organ Chips , Science Officer , Center For Contemporary Sciences ,

Center for Contemporary Sciences (CCS) Partners with BICO to Modernize Medical Research and Drug Development

/PRNewswire/ Today, the Center for Contemporary Sciences (CCS) and BICO formalized a strategic partnership aiming at modernizing drug development and. ....

United States , Erik Gatenholm , Aysha Akhtar , Contemporary Sciences , Cosmetics Act , Organ Chips , Science Officer , Center For Contemporary Sciences ,

Human Organ Chips Shift Amodiaquine from Old Antimalarial to Promising COVID-19 Treatment


Human Organ Chips Shift Amodiaquine from Old Antimalarial to Promising COVID-19 Treatment
May 3, 2021
The ACE2 receptor protein (green), which the SARS-CoV-2 viruses uses to enter cells, is highly expressed on the surfaces of human airway cells grown in the Airway Chip. This faithful mimicking of human biology enables the study of how viruses interact with their hosts cells. [Wyss Institute at Harvard University]
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As the COVID-19 pandemic continues, the pace of vaccine development has surpassed anyone’s wildest expectations. Unfortunately, drug development for treatments has not kept the same pace. Indeed, there are still very few effective treatments for COVID-19. Now, a collaboration between four research institutes has identified the antimalarial drug amodiaquine as a potent inhibitor of SARS-CoV-2 infection in human lung cells and in living preclinical models. This breakthrough helped secure the inclusion of amodiaquine in a COVID-19 clinical trial that ....

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