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Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants


Viral genome sequencing of wastewater can be useful for tracking new SARS-CoV-2 variants
Viral genome sequencing of wastewater can detect new SARS-CoV-2 variants before they are detected by local clinical sequencing, according to a new study reported in
mBio, an open-access journal of the American Society for Microbiology. The ability to track SARS-CoV-2 mutations in wastewater could be particularly useful for tracking new variants, like the B.1.17 strain that is now widespread in the U.K. and has already been introduced in the U.S.
SARS CoV-2 virus is excreted by individuals that are infected by COVID -19and the fecal waste ends up in the wastewater systems. By sampling wastewater, we can get information on infections for a whole population. Some wastewater systems serve several thousand people. Some serve hundreds of thousands of people. Sampling wastewater is a very efficient way to get information. It is also a less biased source of information, because we can get ....

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RECoVERY: New open-source software developed for analyzing SARS-CoV-2 genomes


RECoVERY: New open-source software developed for analyzing SARS-CoV-2 genomes
A team of researchers from the Istituto Superiore di Sanita (ISS), Italy, report an open-source platform-independent tool for building severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genomes from raw sequencing reads. The tool can be used without any extra hardware or software and be run using any browser from a desktop or mobile.
SARS-CoV-2, the causative pathogen of coronavirus disease 2019 (COVID-19) has rapidly spread across the globe resulting in more than two million deaths. Next-generation sequencing technologies (NGS) have allowed complete genome sequencing of the different virus strains, providing estimations of how the virus spreads over time and geographies. ....

Lakshmi Supriya , Phd Jan , Istituto Superiore , Ion Torrent , Genome Detective Virus , Coronavirus Disease Covid 19 , Sars Cov 2 , Corona Virus , Severe Acute Respiratory , Severe Acute Respiratory Syndrome , லட்சுமி சுப்ரியா , ஃப்ட் ஜான் , அயன் நீரோடை , மரபணு துப்பறியும் வைரஸ் , உயிர் தகவலியல் , கொரோனா வைரஸ் , கடுமையானது எடுப்போசை சுவாச , கடுமையானது எடுப்போசை சுவாச நோய்க்குறி ,

Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences


Study shows P681H mutation is becoming globally prevalent among SARS-CoV-2 sequences
In a recent
bioRxiv preprint study, researchers from the University of Hawaii showed that the S gene of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is continuously mutating according to the sequence and phylogenetic analysis. At the same time, a unique strain with an emerging mutation in an altered spike glycoprotein may be present in Hawaii.
Over the past year, there was a notable evolution of SARS-CoV-2 around the globe, which will continue to pose a serious threat. As of January 2021, four novel viral variants have been reported from the United Kingdom (VOC 202012/01/B.1.1.7), South Africa (501Y.V2), Nigeria (B.1.207), and Denmark (Mink Cluster V). ....

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