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Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation. ....

United States , Lily Ramsey , Kumar Sharma , Department Of Medicine , Teresa Lozano Long School Of Medicine , National Institute Of Diabetes , Ut Health San Antonio , Texas Health Science Center , San Antonio , Teresa Lozano Long School , Chronic Renal Insufficiency Cohort , African American , American Indian , Asian Indians , Kidney Precision Medicine Project , National Institute , Kidney Diseases , Precision Medicine , Kidney Failure , Blood Vessels , Kidney Disease , Precision Medicine , Small Molecules ,

Health Beat: Cancer & Organ Transplant Clinic

Studies have shown that organ transplant candidates and recipients have up to a four times increased risk of developing cancer. One clinic has developed a new, unified approach to treating ....

Christopher Blosser , Fred Hutchinson Cancer Center , University Of Washington , Organ Transplant Clinic , Organ Transplantation , Fred Hutchinson Cancer Center , Organ Transplant , Organ Transplant Clinic ,

Acute kidney injury more prevalent amongst extremely premature neonates

1. A secondary analysis of a randomized clinical trial found that when correcting for fluid balance, AKI was more commonly diagnosed in extremely premature neonates. 2. A diagnosis of fluid-corrected AKI resulted in a significantly higher risk of requiring mechanical ventilation, longer hospital stay, and bronchopulmonary dysplasia (BPD). Evidence Rating Level: 1 (Excellent) Acute kidney injury ....

United States , Rating Level , Preterm Erythropoietin Neuroprotection , Acute Kidney Injury , Pediatric Nephrology ,

2 Minute Medicine Rewind August 7, 2023 | 2 Minute Medicine

Fluctuations in Serum Creatinine Levels During Hospitalization and Long-Term End-Stage Kidney Disease and Mortality 1. Despite returning to a normal eGFR at the time of discharge, hospitalized patients with an acute kidney injury (AKI) had increased mortality and morbidity, as well as a greater risk of developing chronic kidney disease, compared to hospitalized patients without ....

United Kingdom , United States , United Kingdom Clinical Practice Research Datalink , Minute Medicine Inc , Rating Level , Lifestyle Study , Hepatitisc Virus , British Columbia , Critical Care , Infectious Diseases , Weekly Rewinds ,

Risk of adverse kidney-related events for patients on lithium is low but increases with greater exposure

1. For patients newly initiated on lithium or valproate, the absolute risks of chronic kidney disease (CKD) progression or acute kidney injury (AKI) were low and similar. 2. Higher cumulative exposure to lithium was associated with greater risk of CKD progression compared to valproate. 3. Higher median lithium levels were associated with increased risk of ....

Ence Rating Level , Acute Kidney Injury , Bipolar Disorder , Chronic Kidney Disease ,