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Scientists grow human tear glands in a lab, and actually make them cry

Scientists grow human tear glands in a lab and actually make them cry
Dutch researchers have an ambitious vision for their organoid.
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- 02:47
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Disembodied human tear glands that cry sound like something out of a sci-fi movie. But in the Netherlands, functional tear glands that don t attach to anyone s eyes (or emotions) are starring in their own real-life drama.
Researchers from the Hubrecht Institute and UMC Utrecht used stem cells to grow tiny tear glands in a petri dish that mimic the real thing. They hope these so-called organoids can serve as models for studying how the cells in human tear glands produce tears. The ultimate goal: to better understand and treat conditions such as dry eye disease or the autoimmune disorder Sjögren s syndrome, as well as cancers of the tear gland. ....

Marie Bannier , Hubrecht Institute , John Hopkins University , Getty Images , Marie Bannier H , Cell Stem , Hans Clever , Health And Wellness , Sci Tech , ஜான் ஹாப்கின்ஸ் பல்கலைக்கழகம் , கெட்டி படங்கள் , செல் தண்டு , ஹான்ஸ் புத்திசாலி , ஆரோக்கியம் மற்றும் ஆரோக்கியம் , அறிவியல் தொழில்நுட்பம் ,

Lab Grown Tear Glands Actually Cries, Simulation Helps Study Sjögren Syndrome

Hubrecht Institute and UMC Utrecht researchers presented lab-grown tear glands using stem cells, simulating the actual ones.
In a CΙNET report, disembodied human tear glands that cry sound is described like something inspired by a sci-fi movie. However, in the Netherlands, functional tear glands not attached to any individual s eyes or even emotions, are said to be stirring in their own real-life drama.
Essentially, the researchers are hoping these so-called organoids can function as models for investigating how the cells in human tear glands are producing tears.
And the ultimate goal, according to the said report, is to better understand the treat health problems like dry eye disease Sjögren s syndrome, an autoimmune disorder, and cancers of the tear gland. The disease is described on Johns Hopkins Rheumatology s YouTube video below. ....

Hans Clevers , Marie Bannier , Hubrecht Institute , John Hopkins University , Johns Hopkins Rheumatology , Grown Tear Glands Presented , Real Ones , Organoid Type Potentially Transplantable , Cell Stem , Lab Grown Tear Glands , Human Tear Glands , Sjorgrens Syndrome , Eye Disease , Ortanoid Potentially Transplantable To Patients , Tear Ducts , Tear Gland Dysfunction , Human Eyes , ஜான் ஹாப்கின்ஸ் பல்கலைக்கழகம் , ஜான்ஸ் ஹாப்கின்ஸ் வாத நோய் , ரியல் ஒன்று , செல் தண்டு , கண் நோய் , கண்ணீர் குழாய்கள் , கண்ணீர் சுரப்பி செயலிழப்பு , மனிதன் கண்கள் ,

Tear glands cry in a dish

Tear glands cry in a dish
Human stem-cell derived organoids make tears.
A confocal image of a mouse lacrimal-gland organoid with the tear product Lcn2 labelled in red, showing that the organoids make tears. Credit: Yorick Post, Hubrecht Institute
A team of researchers, led by Marie Bannier-Hélaouët of the Hubrecht Institute in the Netherlands, has developed organoids that swell up with tears in a petri dish, modelled on tear glands.
This video shows a human organoid, based on tear glands, swelling (i.e. crying) upon the addition of adrenaline. Credit: Marie Bannier-Hélaouët, Hubrecht Institute.
The organoids were made using human stem cells and were able to ‘cry’ in the dish. They also produced tear proteins when transplanted into mice. ....

Marie Bannier , Hubrecht Institute , Marie Bannier H , Cell Stem , செல் தண்டு ,

Scientists grow human tear glands in a lab and actually make them cry

Scientists grow human tear glands in a lab and actually make them cry
CNET
4 days ago
© Provided by CNET
Getty Images
Disembodied human tear glands that cry sound like something out of a sci-fi movie. But in the Netherlands, functional tear glands that don t attach to anyone s eyes (or emotions) are starring in their own real-life drama.
Researchers from the Hubrecht Institute and UMC Utrecht used stem cells to grow tiny tear glands in a petri dish that mimic the real thing. They hope these so-called organoids can serve as models for studying how the cells in human tear glands produce tears. The ultimate goal: to better understand and treat conditions such as dry eye disease or the autoimmune disorder Sjögren s syndrome, as well as cancers of the tear gland. ....

Marie Bannier , Hubrecht Institute , John Hopkins University , Marie Bannier H , Cell Stem , Hans Clever , ஜான் ஹாப்கின்ஸ் பல்கலைக்கழகம் , செல் தண்டு , ஹான்ஸ் புத்திசாலி ,

Crying human tear glands grown in the lab

Credit: Marie Bannier-Hélaouët, copyright Hubrecht Institute
Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so. Scientists everywhere can use the model to identify new treatment options for patients with tear gland disorders, such as dry eye disease. Hopefully in the future, the organoids can even be transplanted into patients with non-functioning tear glands. The results will be published in ....

Helmuth Gehart , Hans Clevers , Marie Bannier , Saskiam Imhof , Marc Trani Bustos , Jeroen Korving , Rachel Kalmann , Harry Begthel , Hans Clevers Hubrecht Institute , Molecular Genetics At Utrecht University , Hubrecht Institute , Cell Stem , Yorick Post , Stem Cell , Pediatric Oncology , Molecular Genetics , Utrecht University , Cell Biology , Medicine Health , மார்க் திரணி பஸ்‌டோஸ் , மூலக்கூறு ஜெநெடிக்ஸ் இல் அட்ரெக்ட் பல்கலைக்கழகம் , செல் தண்டு , தண்டு செல் , குழந்தை புற்றுநோயியல் , மூலக்கூறு ஜெநெடிக்ஸ் , அட்ரெக்ட் பல்கலைக்கழகம் ,