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Crying human tear glands grown in the lab


Credit: Marie Bannier-Hélaouët, copyright Hubrecht Institute
Researchers from the lab of Hans Clevers (Hubrecht Institute) and the UMC Utrecht used organoid technology to grow miniature human tear glands that actually cry. The organoids serve as a model to study how certain cells in the human tear gland produce tears or fail to do so. Scientists everywhere can use the model to identify new treatment options for patients with tear gland disorders, such as dry eye disease. Hopefully in the future, the organoids can even be transplanted into patients with non-functioning tear glands. The results will be published in ....

Helmuth Gehart , Hans Clevers , Marie Bannier , Saskiam Imhof , Marc Trani Bustos , Jeroen Korving , Rachel Kalmann , Harry Begthel , Hans Clevers Hubrecht Institute , Molecular Genetics At Utrecht University , Hubrecht Institute , Cell Stem , Yorick Post , Stem Cell , Pediatric Oncology , Molecular Genetics , Utrecht University , Cell Biology , Medicine Health , மார்க் திரணி பஸ்‌டோஸ் , மூலக்கூறு ஜெநெடிக்ஸ் இல் அட்ரெக்ட் பல்கலைக்கழகம் , செல் தண்டு , தண்டு செல் , குழந்தை புற்றுநோயியல் , மூலக்கூறு ஜெநெடிக்ஸ் , அட்ரெக்ட் பல்கலைக்கழகம் ,

Characterizing different cell types in the upper gastrointestinal tract