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MIS-C in children: A distinct autoimmune response to COVID-19 unveiled

The study reveals that MIS-C patients, post SARS-CoV-2 infection, develop a unique immune response against the virus' N protein, indicating a cross-reactivity with the self-protein SNX8, which might link the infection to the ensuing inflammatory syndrome. ....

Meletios Verras , Image Credit , Coronavirus Disease Covid 19 , Covid 19 , Immune System , Kawasaki Disease , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Researchers discover a highly potent biomarker for clinical response to CAR-T cell therapy

A MedUni Vienna research team has discovered a highly potent biomarker for clinical response to CAR-T cell therapy, describing the prerequisites for optimal use of this novel therapy for lymphoma treatment. ....

Winfried Pickl , Emily Henderson , Institute Of Immunology , Meduni Vienna , Nina Worel , Transfusion Medicine , B Cell , Bell Production , Hodgkin 39s Lymphoma , Non Hodgkin 39s Lymphoma ,

What are the associations of metabolome, microbiome, and immune perturbations with severe COVID-19?

In a new study, researchers observed that coronavirus disease 2019 (COVID-19) progression and inflammatory responses are associated with changes in the metabolome and microbiome. ....

Discovery Industry Focus , Coronavirus Disease Covid 19 , Covid 19 , Acute Respiratory Distress Syndrome , Immune Response ,

Comprehensive analysis outlines the potential toxicities of antibody drug conjugates

Over the past two decades, numerous complex cancer therapies called antibody drug conjugates (ADCs) have been tested in clinical trials and approved for use in patients. ....

United States , Chong Zhu , Emily Henderson , Central South University , Drug Administration , American Cancer Society , American Cancer , Xiangya Hospital ,

COVID-19 and the gut

Researchers summarize current knowledge about underlying mechanisms and potential therapeutic approaches for the effects of COVID-19 on the gut. ....

Image Credit , Genomics Industry Focus , Coronavirus Disease Covid 19 , Abdominal Pain , Fatty Acids , Immune Response , Immune System , Respiratory Disease , Ibonucleic Acid , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,