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Combination therapy overcomes BET inhibitor resistance

Combination therapy overcomes BET inhibitor resistance
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Researchers speed identification of DNA regions that regulate gene expression

St. Jude Children s Research Hospital scientists have developed an integrated, high-throughput system to better understand and possibly manipulate gene expression to treat disorders such as sickle cell disease and beta-thalassemia. The research appears today in the journal Nature Genetics.

Mouse model reveals how RNA splicing defects contribute to neurodegeneration in Alzheimer s disease

Researchers have puzzled over the neurodegenerative disorder Alzheimer's disease for decades, but treatments to stop or reverse the disease's effects on the brain have remained elusive.

Model demonstrates how RNA splicing defects contribute to Alzheimer s disease

Scientists at St. Jude Children’s Research Hospital created a model to study the role of RNA splicing defects in Alzheimer’s disease, revealing degeneration

Model demonstrates how RNA splicing defects contribute to Alzheimer s

Model demonstrates how RNA splicing defects contribute to Alzheimer s
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