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Unveiling Why Childhood Cancer Resists Chemotherapy

Unveiling Why Childhood Cancer Resists Chemotherapy
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United statesJonathan diedrichJackson mobleyBrennan bergeronDaniel savicSteven kornblauBaranda hansenShondra pruett millerElisabeth paiettaWilliam evansHiroto inabaMark litzowWenjian yangMary rellingJun yangSima jeha

Novel therapeutic approach identified for overcoming resistance in B-cell leukemia

Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between 30-50%.

United statesXin huangXu yangCharles mullighanSeth karolSteven kornblauJunj yangXiaofan zhuSheetal bhataraYizhen liYingchi zhangSatoshi yoshimuraNitin jainJiyang yuMarina konoplevaJingliao zhang

Novel Drug Combo Targets B-cell Vulnerability to Treat Leukemia

Novel Drug Combo Targets B-cell Vulnerability to Treat Leukemia
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Xu yangUnited statesXin huangJingliao zhangWilliam evansElias jabbourHiroto inabaCharles mullighanSeth karolYizhen liWenjian yangMark litzowSatoshi yoshimuraNitin jainHuanbin zhaoMarina konopleva

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
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Xu yangXin huangUnited statesMark litzowHuanbin zhaoSatoshi yoshimuraElias jabbourXiaofan zhuYizhen liYingchi zhangJingliao zhangSheetal bhataraSteven kornblauNitin jainWilliam evansSeth karol

Targeting vulnerability in B-cell development leads to novel drug combination for leukemia

Xu yangUnited statesXin huangSeth karolWilliam evansWenjian yangSheetal bhataraJingliao zhangYingchi zhangSteven kornblauNitin jainCharles mullighanHiroto inabaElisabeth paiettaMarina konoplevaSatoshi yoshimura