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The disruption of gene transcription and cell function in Down syndrome is very similar to that seen in cellular aging, MIT scientists find. They used anti-senescence drugs to correct the errors in cell cultures, establishing senescence as a potentially targetable mechanism for future treatment. ....

United States , Ashley Watson , Lindsey Guerin , Angelika Amon , Asaf Marco , Vishnu Dileep , Hiruy Meharena , Jacob Jaffe , Li Huei Tsai , Shruti Rengarajan , Malvina Papanastasiou , Elana Lockshin , Fatema Abdurrob , James Mullahoo , Alana Down Syndrome Center , Burroughs Wellcome Fund , Lumind Foundation , National Institutes Of Health , Jalana Center , Picower Institute For , Alana Foundation , University Of California At San Diego , Cell Stem , Senior Alana Fellow , Picower Professor , Picower Institute ,