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Light-Activated Drug Induces Sleep by Targeting Specific Brain Region

Light-Activated Drug Induces Sleep by Targeting Specific Brain Region
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Tsuyoshi Saitoh , Michael Lazarus , International Institute For Integrative Sleep Medicine , Nature Communications , Institute Of Medicine , University Of Tsukuba , International Institute , Integrative Sleep Medicine ,

Novel light-sensitive drug induces sleep without genetic modification

The nucleus accumbens plays a pivotal role in motivational behavior and sleep regulation, modulated by adenosine A2A receptors (A2AR). ....

Tsuyoshi Saitoh Tri , Michael Lazarus , University Of Tsukuba , International Institute For Integrative Sleep Medicine , Technology Agency , World Premier International Research Center Initiative , Scientific Research , Institute Of Medicine , Integrative Sleep , Professor Michael Lazarus , Associate Professor Tsuyoshi Saitoh , International Institute , Integrative Sleep Medicine , Japan Science ,

Study develops light-activated drug targeting receptors in the brain that induce sleep

Adenosine A2A receptors (A2AR) in the nucleus accumbens of the brain play an important role in regulating sleep and motivation, but until now, no drugs have been able to selectively modulate their function without affecting other organs or brain areas. In a recent study, a light-activated allosteric modulator of A2AR was developed and successfully used to remotely induce sleep by selective light irradiation of the nucleus accumbens in mice. ....

Koustav Roy , Tsuyoshi Saitoh Tri , Michael Lazarus , University Of Tsukuba , Institute Of Medicine , Nature Communications , International Institute For Integrative Sleep Medicine , Professor Michael Lazarus , Associate Professor Tsuyoshi Saitoh , International Institute , Integrative Sleep Medicine ,

'A huge mistake': Japan's sleeplessness crisis poses threat to society, warns leading expert

Ministry of Health study highlights severe lack of sleep among Japanese, raising alarms over potential societal impacts. ....

Izumi Tsuji , University Of Tokyo , Tokyo Chuo University , Chuo University , Alzheimer X27s Disease , Chuo University , International Institute For Integrative Sleep Medicine , Izumi Tsuji , Masashi Yanagisawa , Ministry Of Health , Organization For Economic Cooperation And Development , University Of Tsukuba , Sleep Deprivation ,

Japan's sleep-deprived employees embrace the workplace nap – DW – 10/06/2023

Government and experts warn that Japanese people are not getting enough good quality sleep, risking health issues, irritation and a loss of focus at work. ....

Michihiro Fukano , Masashi Yanagisawa , Koyoju Plywood Corp , National University Of Singapore , International Institute For Integrative Sleep Medicine , Oura Health Oy , University Of Tsukuba , Organization For Economic Cooperation , Economic Cooperation , National University , International Institute , Integrative Sleep Medicine , Hokkaido Based Koyoju Plywood Corp ,