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Possible origin of neuroblastoma in the adrenal glands discovered


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Neuroblastoma is a childhood cancer, most commonly affecting children aged between 2 -3 and can be fatal. Since the tumour cells resemble certain cells in the adrenal glands, a joint research group from MedUni Vienna s Center for Brain Research and the Swedish Karolinska Institute investigated the cellular origin of these cells and sympathetic neurons during the embryonic development of human adrenal glands. During the course of their investigations, they discovered a previously unknown cell type that might potentially be the origin of the tumour cells.
Treatments for this disease are extremely aggressive and challenging and relapses are not uncommon. So far, little is known about the origins of this cancer or the causes of relapse. However, it is assumed that neuroblastomas are due to abnormalities in the neural crest cells, which form the peripheral nervous system during embryogenesis. ....

Igor Adameyko , Swedish Karolinska Institute , Brain Research , Meduni Vienna Center , Meduni Vienna , மூளை ஆராய்ச்சி ,

ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology


ALSF announces grant award recipients of Crazy 8 Initiative in pediatric oncology
Alex s Lemonade Stand Foundation (ALSF), a nonprofit foundation devoted to finding cures for all children with cancer, announces grant award recipients of their Crazy 8 Initiative. The recipients will receive grants totaling more than $18.5 million, which is the single, largest funding commitment from ALSF to date.
The Initiative kicked off in the Fall of 2018 with a meeting that brought together more than 90 scientists from around the world to help define the research landscape in eight key areas of need in order to tackle major obstacles impeding progress toward cures for childhood cancer. Through a rigorous review process, ALSF received over 100 letters of intent from researchers that resulted in 83 full grant applications which were ultimately narrowed down to four projects that will work to accelerate the pace of new cure discovery. ....

United States , Seychelle Vos , Yaelp Moss , Jefferym Klco , Leonard Zon , Ross Levine , Emily Henderson , Klimenta Verba , Liz Scott , Zoran Rankovic , Peter Campbell , Igor Adameyko , Martin Eilers , Matthias Farlik , Martin Distel , Scotta Armstrong , Paula Northcott , Fernando Camargo , John Maris , Natalia Jura , Gwenn Hansen , Florian Halbritter , Charlesg Mullighan , Williama Weiss , M Madan Babu , Juerg Schwaller ,

Alex's Lemonade Stand Foundation awards more than $18.5 million

Alex's Lemonade Stand Foundation awards more than $18.5 million
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United States , Seychelle Vos , Yaelp Moss , Jefferym Klco , Leonard Zon , Ross Levine , Klimenta Verba , Liz Scott , Zoran Rankovic , Peter Campbell , Igor Adameyko , Martin Eilers , Matthias Farlik , Martin Distel , Scotta Armstrong , Paula Northcott , Fernando Camargo , John Maris , Natalia Jura , Gwenn Hansen , Florian Halbritter , Charlesg Mullighan , Williama Weiss , M Madan Babu , Juerg Schwaller , Vijayg Sankaran ,