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Researchers Unlock Genomic Secrets of Gutless Deep-sea Tubeworm


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Researchers Unlock Genomic Secrets of Gutless Deep-sea Tubeworm
Researchers from The Hong Kong University of Science and Technology (HKUST) decoded for the first time the chromosomal-level genome of a deep-sea gutless tubeworm and how the worm’s co-living bacterial partners manufacture organic nutrients for its host so it can survive the extreme habitat. The discovery lays foundation for potential applications such as biomaterial production and microbial growth control.
Tubeworms are present as large habitat-forming chitinized tube bushes in the deep-sea, where photosynthesis-derived organic matter are scarce.
Living in deep-sea hydrothermal vents and cold seeps ecosystems characterized by darkness, high pressure and often high concentrations of toxic substances, submarine tubeworms – common living organisms of such extreme environments, were known to owe their survival and fast growth to sulphide-oxidising symbiotic bacteria that live inside their bo ....

Hong Kong , South China Sea , Brunei General , Department Of Ocean Science , Hong Kong University Of Science , Hong Kong University , Chair Professor , Ocean Science , Hong Kong Baptist University , South China , Hansemann Professor , Molecular Biology , ஹாங் காங் , தெற்கு சீனா கடல் , துறை ஆஃப் கடல் அறிவியல் , ஹாங் காங் பல்கலைக்கழகம் ஆஃப் அறிவியல் , ஹாங் காங் பல்கலைக்கழகம் , நாற்காலி ப்ரொஃபெஸர் , கடல் அறிவியல் , ஹாங் காங் ஞானஸ்நானம் பல்கலைக்கழகம் , தெற்கு சீனா , மூலக்கூறு உயிரியல் ,

Researchers unravel how a novel microbial small molecule is connected to dental caries development


Researchers unravel how a novel microbial small molecule is connected to dental caries development
An inter-disciplinary team of researchers led by Prof. Qian Peiyuan, Chair Professor at the Hong Kong University of Science and Technology (HKUST) s Department of Ocean Science and Division of Life Science has unraveled how a novel microbial small molecule released by Streptococcus mutans (S. mutans) - a bacterium commonly found in the human oral cavity - is connected to dental caries development using a synthetic biology approach, offering new insights to the health impact of the human oral microbiota and facilitating future research on the prevention of tooth decay. ....

Hong Kong , Qian Peiyuan , Emily Henderson , Division Of Life Science , College Of Dentistry , Department Of Ocean Science , National Institutes Of Health , University Of California At Berkeley , University Of Florida , Hong Kong University Of Science , Chair Professor , Hong Kong University , Ocean Science , Life Science , Nature Chemical Biology , National Institutes , Hansemann Professor , Tooth Decay , ஹாங் காங் , எமிலி ஹென்டர்சன் , பிரிவு ஆஃப் வாழ்க்கை அறிவியல் , கல்லூரி ஆஃப் பல் மருத்துவம் , துறை ஆஃப் கடல் அறிவியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா இல் பெர்க்லி , பல்கலைக்கழகம் ஆஃப் புளோரிடா ,

HKUST researchers unlock the micro-molecular physiochemical mechanism of dental plaque formation


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IMAGE: (Left up panel) Effect of biosynthetic gene cluster muf or mutanofactin-697 (5) on biofilm formation on the surface of artificial acryl teeth. (Left bottom panel) Proposed biosynthetic pathway for mutanofactin-697.
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Credit: HKUST
An inter-disciplinary team of researchers led by Prof. Qian Peiyuan, Chair Professor at the Hong Kong University of Science and Technology (HKUST) s Department of Ocean Science and Division of Life Science has unraveled how a novel microbial small molecule released by Streptococcus mutans (S. mutans) - a bacterium commonly found in the human oral cavity - is connected to dental caries development using a synthetic biology approach, offering new insights to the health impact of the human oral microbiota and facilitating future research on the prevention of tooth decay. The research findings were recently published in the prestigious scientific journal ....

Hong Kong , Qian Peiyuan , Division Of Life Science , College Of Dentistry , Department Of Ocean Science , National Institutes Of Health , University Of California At Berkeley , University Of Florida , Hong Kong University Of Science , Chair Professor , Hong Kong University , Ocean Science , Life Science , Nature Chemical Biology , National Institutes , Hansemann Professor , Molecular Biology , Dentistry Periodontal Disease , ஹாங் காங் , பிரிவு ஆஃப் வாழ்க்கை அறிவியல் , கல்லூரி ஆஃப் பல் மருத்துவம் , துறை ஆஃப் கடல் அறிவியல் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா இல் பெர்க்லி , பல்கலைக்கழகம் ஆஃப் புளோரிடா , ஹாங் காங் பல்கலைக்கழகம் ஆஃப் அறிவியல் ,