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City scientists patent asthma breakthrough - Innovation Toronto

City scientists patent asthma breakthrough - Innovation Toronto
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New Zealand , New Zealand General , New Zealanders , Franca Ronchese , Ian Hermans , Malaghan Institute , Victoria University Ferrier Research Institute , Liam Kennedy Clark , Nature Chemical Biology , Victoria University , Ferrier Research ,

Antibody–peptide inhibitor conjugates: A new path for cancer therapy

Tumor cells often hijack normal physiological processes to support their growth, exploiting proteins that are in charge of essential cell functions. It is therefore important to block the activity of these proteins only in cancer cells without affecting their crucial roles in healthy tissues. For this reason, classical approaches using small molecules that induce systemic inhibition across all cells in the body can lead to severe side effects. ....

Bruno Correia , Elisa Oricchio , Aaron Petruzzella , Nature Chemical Biology , Nature Chemical ,