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Moderate Aortic Stenosis and HFrEF Combo Portends Poor Survival, Study Finds

June 03, 2021
Accumulating data make clear the detrimental effect of moderate aortic stenosis (AS) in patients who have heart failure with reduced ejection fraction (HFrEF), a new study suggests, and they point toward the potential for improving survival after TAVI.
Compared with patients who had HFrEF but not moderate AS, those with the combination of both had greater risk for mortality at 3 years (HR 2.98; 95% CI 2.08-4.31), as well as for the composite of HF hospitalization and mortality (HR 2.34; 95% CI 1.72-3.21). Additionally, those who had TAVI over the follow-up period survived longer than those on medication alone.
Senior author Marie-Annick Clavel, PhD (Laval University, Quebec, Canada), said the while there is consensus that moderate aortic stenosis is not benign, optimal management for the subset of patients with both HF and moderate aortic stenosis is unclear. However, she said current thinking seems to be moving away from “wait-and-see” approaches to ....

United States , Nilayk Patel , Sammy Elmariah , Guillaume Jean , Marie Annick Clavel , Journal Of The American College Cardiology , Md Laval University , Phd Laval University , Laval University , American College , Provide More , Massachusetts General Hospital , ஒன்றுபட்டது மாநிலங்களில் , கிலௌம் ஜீன் , இதழ் ஆஃப் தி அமெரிக்கன் கல்லூரி இருதயவியல் , ம்ட் லாவள் பல்கலைக்கழகம் , லாவள் பல்கலைக்கழகம் , அமெரிக்கன் கல்லூரி , வழங்க மேலும் , மாசசூசெட்ஸ் ஜநரல் மருத்துவமனை ,

Moderate Aortic Stenosis and HFrEF Combo Portend Poor Survival, Study Finds

Valve replacement, particularly TAVI, showed promise as an early intervention, but a randomized trial is ongoing. ....

United States , Nilayk Patel , Sammy Elmariah , Guillaume Jean , Marie Annick Clavel , Journal Of The American College Cardiology , Md Laval University , Phd Laval University , Laval University , American College , Provide More , Massachusetts General Hospital , ஒன்றுபட்டது மாநிலங்களில் , கிலௌம் ஜீன் , இதழ் ஆஃப் தி அமெரிக்கன் கல்லூரி இருதயவியல் , ம்ட் லாவள் பல்கலைக்கழகம் , லாவள் பல்கலைக்கழகம் , அமெரிக்கன் கல்லூரி , வழங்க மேலும் , மாசசூசெட்ஸ் ஜநரல் மருத்துவமனை ,